A0A2T6IK68 · A0A2T6IK68_TOXGO

  • Protein
    Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functiondiphosphoinositol-pentakisphosphate kinase activity
Molecular Functioninositol heptakisphosphate kinase activity
Molecular Functioninositol hexakisphosphate 1-kinase activity
Molecular Functioninositol hexakisphosphate 3-kinase activity
Molecular Functioninositol hexakisphosphate 5-kinase activity
Molecular Functioninositol-1,3,4,5,6-pentakisphosphate kinase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
  • EC number

Gene names

    • ORF names
      TGBR9_304650B

Organism names

  • Taxonomic identifier
  • Strain
    • TgCATBr9
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Sarcocystidae > Toxoplasma

Accessions

  • Primary accession
    A0A2T6IK68

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias76-134Polar residues
Region76-139Disordered
Region166-341Disordered
Compositional bias201-215Basic and acidic residues
Compositional bias229-248Basic and acidic residues
Compositional bias297-311Polar residues
Region427-480Disordered
Compositional bias433-447Polar residues
Region527-652Disordered
Compositional bias536-582Polar residues

Sequence similarities

Belongs to the histidine acid phosphatase family. VIP1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    689
  • Mass (Da)
    72,020
  • Last updated
    2018-07-18 v1
  • Checksum
    9DACD6B4DCEAC310
MGRALCCGFDILRTSSGPFVCDVNGFSFVKGNVKYYEDCANILRLFFIKKSIERWSAFGVSPQLAAPLADSTPAACAQGAGTSASGSSDPRGGPPRSTDPTETFVTGSNTELQLVAASPPSASSASFASPSPLFRASSPSPPLHIVLQQLLRARNEYRAQRQICREEEKRRERQTAEADLRLPAAAASSGGSSPEGVLGGRALLEDEKQFRREGGKTGGDPASAAESQDVCRSRKETGEQRKEHKRTPSSGSSPLCLAGLPSRETRMHAPAVGSEETVAAREARRGFGVGEDSPQDGALSPSFSSFSVSHAPLETDPPEDRAGTMSPYTTAGEASGDDDEELRTVVVVMRHGDRKPKQKLKFKTDQDLILELFDEERNRRKEIKLKSPEELRDLLDRNTEIITFLGKKMMSLVADKKSLDEQKAVLEARAASPSPSASCSACASPDSASAEASDPGASGHVSSGGAGEEDSVGLTREAQGLQTALEKKEAAIAKLQKELSAHKQLQKVLLQGDGFAGINRKIQLKPIEWEETGSPRVASSHVSTASSASSSSSSSSSSSCASSSESTSASASSSSSASPSVLSGEARVGVGGHCGEAGMQSSAKGKGEKTKPRGASGQMPVESATSSSASPAPPSPPPLSSSGAAGTAAGPPGRVMRCVVVAKWGGELTGIGRKQAEDLGKKFRYKLYP

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias76-134Polar residues
Compositional bias201-215Basic and acidic residues
Compositional bias229-248Basic and acidic residues
Compositional bias297-311Polar residues
Compositional bias433-447Polar residues
Compositional bias536-582Polar residues
Non-terminal residue689

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AFHV02002677
EMBL· GenBank· DDBJ
PUA85732.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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