A0A2T3KHQ6 · A0A2T3KHQ6_9GAMM
- ProteinBifunctional aspartokinase/homoserine dehydrogenase
- GenemetL
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids804 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-aspartate + ATP = 4-phospho-L-aspartate + ADP
Cofactor
Pathway
Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aspartate kinase activity | |
Molecular Function | ATP binding | |
Molecular Function | homoserine dehydrogenase activity | |
Molecular Function | NADP binding | |
Biological Process | homoserine biosynthetic process | |
Biological Process | lysine biosynthetic process via diaminopimelate | |
Biological Process | phosphorylation | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBifunctional aspartokinase/homoserine dehydrogenase
Including 2 domains:
- Recommended nameAspartokinase
- EC number
- Recommended nameHomoserine dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Photobacterium
Accessions
- Primary accessionA0A2T3KHQ6
Proteomes
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-277 | Aspartate/glutamate/uridylate kinase | |||
Domain | 459-593 | Aspartate/homoserine dehydrogenase NAD-binding | |||
Domain | 602-797 | Homoserine dehydrogenase catalytic | |||
Sequence similarities
In the C-terminal section; belongs to the homoserine dehydrogenase family.
In the N-terminal section; belongs to the aspartokinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length804
- Mass (Da)88,110
- Last updated2018-07-18 v1
- ChecksumB410001D844B814F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PYNF01000008 EMBL· GenBank· DDBJ | PSU98703.1 EMBL· GenBank· DDBJ | Genomic DNA |