A0A2S8DSJ9 · A0A2S8DSJ9_SHIBO

  • Protein
    Beta-barrel assembly-enhancing protease
  • Gene
    bepA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

148750100150200250300350400450
Type
IDPosition(s)Description
Binding site136Zn2+ (UniProtKB | ChEBI); catalytic
Active site137
Binding site140Zn2+ (UniProtKB | ChEBI); catalytic
Binding site201Zn2+ (UniProtKB | ChEBI); catalytic
Active site205Proton donor

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentperiplasmic space
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processchaperone-mediated protein folding
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Beta-barrel assembly-enhancing protease
  • EC number

Gene names

    • Name
      bepA
    • ORF names
      NCTC8576_05074

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCTC8576
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Shigella

Accessions

  • Primary accession
    A0A2S8DSJ9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-27
ChainPRO_503167944028-487Beta-barrel assembly-enhancing protease

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain71-259Peptidase M48

Sequence similarities

Belongs to the peptidase M48 family. BepA subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    487
  • Mass (Da)
    53,949
  • Last updated
    2018-07-18 v1
  • MD5 Checksum
    2E82F23786EED36132008D31F87EBF1A
MFRQLKKNLVATLIAAMTIGQVAPAFADNADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHLTQRHLARAMEDQQRSAPLTWVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UAUR01000009
EMBL· GenBank· DDBJ
SPZ89172.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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