A0A2S6CP70 · A0A2S6CP70_9CYAN

Function

function

Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site12-17NAD+ (UniProtKB | ChEBI)
Binding site16NADPH (UniProtKB | ChEBI)
Binding site36NADPH (UniProtKB | ChEBI)
Binding site37NADPH (UniProtKB | ChEBI)
Binding site86NADPH (UniProtKB | ChEBI)
Binding site86sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site86substrate
Binding site114sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site118NADPH (UniProtKB | ChEBI)
Active site169Proton acceptor
Binding site169sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site222sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site232sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site233NAD+ (UniProtKB | ChEBI)
Binding site233NADPH (UniProtKB | ChEBI)
Binding site233sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site233-234substrate
Binding site234sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site259NADPH (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglycerol-3-phosphate dehydrogenase (NADP+) activity
Molecular Functionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Molecular FunctionNAD binding
Biological Processcarbohydrate metabolic process
Biological Processglycerol-3-phosphate biosynthetic process
Biological Processglycerol-3-phosphate catabolic process
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Alternative names
    • NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase
    • NAD(P)H-dependent dihydroxyacetone-phosphate reductase

Gene names

    • Name
      gpsA
    • ORF names
      CUN59_20575

Organism names

Accessions

  • Primary accession
    A0A2S6CP70

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-37Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Domain41-136Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Domain158-298Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    325
  • Mass (Da)
    35,086
  • Last updated
    2018-07-18 v1
  • Checksum
    0169DEF2A8615657
MNNKPQNITILGAGAWGQALAHLAAINQHTVRLWSRHSPVSLEDTLANTDIILCAISMKGVRDVANLVNSVNEKSLKNTIVVTATKGLEPYTTYTPSQIWETIFPHQPVVVLSGPNLSKEIEQKLPAATVVASKNVVAAQQIQLVFSSQQFRVYTNPDPVGVELGGTLKNVIAISAGVCDGLHLGTNAKAALVTRGLTEMVRIGNTLGAKTETFYGLSGLGDLLATCNSPLSRNYQVGYQLANSKTLPEVLSSLSGTAEGVNTCRVLMEIAQKHSIAIPITEQVYQLLAGEITPRQALDKLMLRDIKSEFDNFPVEQIWSRGEKC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PGEM01000218
EMBL· GenBank· DDBJ
PPJ61502.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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