A0A2S5W2N7 · A0A2S5W2N7_9MICO
- ProteinPurine nucleoside phosphorylase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids278 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.
Catalytic activity
- a purine 2'-deoxy-D-ribonucleoside + phosphate = a purine nucleobase + 2-deoxy-alpha-D-ribose 1-phosphate
Pathway
Purine metabolism; purine nucleoside salvage.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 45 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 77 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 98-100 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 130 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 199 | a purine D-ribonucleoside (UniProtKB | ChEBI) | |||
Binding site | 218 | phosphate (UniProtKB | ChEBI) | |||
Binding site | 241 | a purine D-ribonucleoside (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | purine-nucleoside phosphorylase activity | |
Biological Process | nucleoside metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePurine nucleoside phosphorylase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Subtercola
Accessions
- Primary accessionA0A2S5W2N7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homotrimer.
Structure
Sequence
- Sequence statusComplete
- Length278
- Mass (Da)28,993
- Last updated2018-07-18 v1
- ChecksumB617C70271934FF7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PSTT01000071 EMBL· GenBank· DDBJ | PPF82147.1 EMBL· GenBank· DDBJ | Genomic DNA |