A0A2S5W2N7 · A0A2S5W2N7_9MICO

  • Protein
    Purine nucleoside phosphorylase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; purine nucleoside salvage.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site45phosphate (UniProtKB | ChEBI)
Binding site77phosphate (UniProtKB | ChEBI)
Binding site98-100phosphate (UniProtKB | ChEBI)
Binding site130phosphate (UniProtKB | ChEBI)
Binding site199a purine D-ribonucleoside (UniProtKB | ChEBI)
Binding site218phosphate (UniProtKB | ChEBI)
Binding site241a purine D-ribonucleoside (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpurine-nucleoside phosphorylase activity
Biological Processnucleoside metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Purine nucleoside phosphorylase
  • EC number
  • Alternative names
    • Inosine-guanosine phosphorylase

Gene names

    • ORF names
      C5B96_09300

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Z020
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Subtercola

Accessions

  • Primary accession
    A0A2S5W2N7

Proteomes

Subcellular Location

Interaction

Subunit

Homotrimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain39-275Nucleoside phosphorylase

Sequence similarities

Belongs to the PNP/MTAP phosphorylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    278
  • Mass (Da)
    28,993
  • Last updated
    2018-07-18 v1
  • Checksum
    B617C70271934FF7
MSSAAAQNPLDQPDLSPFEIAREAAGQIAEKSGIAQHDIALTLGSGWAKAADLIGETVATIPATEIVGFSAPAVVGHVGSLRSVRLPNGKHALVIGARTHYYENHGVRRVVHSVRTAAAAGAKVMILTNGAGGIRETWKPGSPVLISDHINLTADSPLEGATFIDLTDLYSKRLRDIARGVDAGLDEGVYVQFRGPHYETPAEVQMAKTIGGHIVGMSTALEAIAAREAGMEVLGMSLITNLAAGIQKTPLSHKEVLEAGQQAEPVISALLARIVAAL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PSTT01000071
EMBL· GenBank· DDBJ
PPF82147.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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