A0A2S5UWR3 · A0A2S5UWR3_9MICO
- ProteinUDP-glucose 6-dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids435 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- UDP-alpha-D-glucose + 2 NAD+ + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H+
Pathway
Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 30 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 35 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 85 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 121 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 147-150 | substrate | |||
Binding site | 150 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 206 | substrate | |||
Binding site | 251-255 | substrate | |||
Binding site | 259 | substrate | |||
Active site | 262 | Nucleophile | |||
Binding site | 265 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 325 | substrate | |||
Binding site | 332 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | NAD binding | |
Molecular Function | UDP-glucose 6-dehydrogenase activity | |
Biological Process | polysaccharide biosynthetic process | |
Biological Process | UDP-glucuronate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-glucose 6-dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Pseudoclavibacter
Accessions
- Primary accessionA0A2S5UWR3
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 318-418 | UDP-glucose/GDP-mannose dehydrogenase C-terminal | |||
Sequence similarities
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length435
- Mass (Da)46,121
- Last updated2018-07-18 v1
- ChecksumB8E8223E027D959A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PSTQ01000014 EMBL· GenBank· DDBJ | PPF42405.1 EMBL· GenBank· DDBJ | Genomic DNA |