A0A2S5R6M1 · A0A2S5R6M1_9PROT

Function

function

The main replicative DNA helicase, it participates in initiation and elongation during chromosome replication. Travels ahead of the DNA replisome, separating dsDNA into templates for DNA synthesis. A processive ATP-dependent 5'-3' DNA helicase it has DNA-dependent ATPase activity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentprimosome complex
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Molecular FunctionDNA helicase activity
Biological ProcessDNA replication, synthesis of primer
Biological ProcessDNA unwinding involved in DNA replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Replicative DNA helicase
  • EC number

Gene names

    • ORF names
      HCUR_01587

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 02AZ16
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Holosporales > Holosporaceae > Holospora

Accessions

  • Primary accession
    A0A2S5R6M1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain183-475SF4 helicase

Sequence similarities

Belongs to the helicase family. DnaB subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    478
  • Mass (Da)
    53,520
  • Last updated
    2018-07-18 v1
  • Checksum
    45658D0DF08FC456
MSVTPTLPQTPYNLEIEQSLLSILLRNNSVFEDIGETLHPEYFYTSLHQHIFKTLSHLIRKGQIANPITLKHYVENYLQGDDVGLSDTYLAELVGLLVPTRNALYYVKVIYDLYLRRQLASLGEDISYAAGVMDVEGPDAIQQIEIAENQLFQMHKESAKSQVYSFAFALTQAIESAQLAYQRDSHVVGVSTGLLDLDKMLGGLHPSDLVILAARPAMGKTALATNIAFNAARLKMRDTENKGDGAGVGFFSLEMSALQLAMRIIAQETGVSSDRMRRGAIDKEAFPLFVDLSKELAALPLFIDDTPALSVTSLLTRARRLQRKENIKLIVVDYLQLLTTGKSNSENRVQELSEITRGLKQMAKTLNVPVLALSQLSRAVEQREDKRPMLADLRESGSIEQDADVVMFIYREEYYEARNKPQEGSEKMIHWQRHMAEIYNSAEVIIAKQRHGPTGSVFLQFDGGRTKFSNAASKTINF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PHHC01000151
EMBL· GenBank· DDBJ
PPE02979.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp