A0A2S5E5W3 · A0A2S5E5W3_9BURK
- ProteinFormyltetrahydrofolate deformylase
- GenepurU
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids294 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
Catalytic activity
- (6R)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H+
Pathway
Purine metabolism; IMP biosynthesis via de novo pathway; formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 238 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | formyltetrahydrofolate deformylase activity | |
Biological Process | 'de novo' IMP biosynthetic process | |
Biological Process | one-carbon metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFormyltetrahydrofolate deformylase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex
Accessions
- Primary accessionA0A2S5E5W3
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length294
- Mass (Da)32,937
- Last updated2018-07-18 v1
- Checksum151BFDF175D95476
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PQVP01000001 EMBL· GenBank· DDBJ | POZ86790.1 EMBL· GenBank· DDBJ | Genomic DNA |