A0A2S5DPE2 · A0A2S5DPE2_9BURK

Function

function

Extracellular zinc metalloprotease.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for active site.

156550100150200250300350400450500550
TypeIDPosition(s)Description
Active site377
Active site465Proton donor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Neutral metalloproteinase
  • EC number

Gene names

    • ORF names
      C3743_35245

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 170816
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex

Accessions

  • Primary accession
    A0A2S5DPE2

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_502315819725-565Neutral metalloproteinase

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain70-116FTP
Domain222-384Peptidase M4
Domain387-564Peptidase M4 C-terminal

Sequence similarities

Belongs to the peptidase M4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    565
  • Mass (Da)
    59,733
  • Last updated
    2018-07-18 v1
  • Checksum
    87B6210E38560560
MKKLSRLLSISAITVASLSAFAQAGDPSAAVDKALQLIQQNPSAFSLAAGGAARTLKFAGPQASAPADGDQFQVRDVIVDPDGTEHVRFDRFHASLPVIGGDVVVHSRNGQLKQASVTQLAPINLAGTIGKVGNRAVVRNAPDIGAARVKRIAAARFNSDVRRVEDAELVVFARDVTPTLAYAVRVYGKATDVHGDAVLYYVDARTGTVLDAQDLIKTAAATGTGRSLYYGNLTLTTDQTGTNAYRMLDPSRGSGSVYDGRGLTSDDVEQATDLPIFTSSTNVWGNNTTTDRQTVAADIDYGLALTWDYYKTAHNRNGIFNDGRGVKSYAHVVFNTGSGTTGANAAWLDSHVMVYGDGQPGTSLPKPVVSVDVAGHEMSHGVTEATANLNYSGDAGGLNESTSDIFGTLVKYYANNPNDPGNYVIGARVVSGGLRKMYKQDLDGRSFSCYPSGGFSWSNPRHDPHFTSGVGNRLFYLLAEGPTVPSTDTGLTKAQLVCNGDTTFSGVGREKAGKIWYRTLTVYLNANSSYPSARRASIQAANDLYGANSAESAAVARAWSAVGVN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PQVP01000003
EMBL· GenBank· DDBJ
POZ80912.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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