A0A2S5DN86 · A0A2S5DN86_9BURK
- ProteinAcetate kinase
- GeneackA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids399 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
Catalytic activity
- acetate + ATP = acetyl phosphate + ADP
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Mg2+. Can also accept Mn2+.
Pathway
Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 10 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 17 | ATP (UniProtKB | ChEBI) | |||
Binding site | 92 | substrate | |||
Active site | 149 | Proton donor/acceptor | |||
Site | 180 | Transition state stabilizer | |||
Binding site | 207-211 | ATP (UniProtKB | ChEBI) | |||
Site | 240 | Transition state stabilizer | |||
Binding site | 282-284 | ATP (UniProtKB | ChEBI) | |||
Binding site | 330-334 | ATP (UniProtKB | ChEBI) | |||
Binding site | 381 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | acetate kinase activity | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Biological Process | acetate metabolic process | |
Biological Process | acetyl-CoA biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex
Accessions
- Primary accessionA0A2S5DN86
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length399
- Mass (Da)41,761
- Last updated2018-07-18 v1
- Checksum4B493407E8758FC8
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PQVP01000003 EMBL· GenBank· DDBJ | POZ80568.1 EMBL· GenBank· DDBJ | Genomic DNA |