A0A2S2QPA9 · A0A2S2QPA9_9HEMI

Function

Catalytic activity

  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-sn-glycerol + ATP = 1-hexadecanoyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + ATP = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • N-(hexanoyl)sphing-4-enine + ATP = N-hexanoylsphing-4-enine 1-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.107 (UniProtKB | ENZYME | Rhea)
  • a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a 2-acylglycerol + ATP = a 2-acyl-sn-glycerol 3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
  • a monoacylglycerol + ATP = a monoacyl-sn-glycero-3-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.94 (UniProtKB | ENZYME | Rhea)
  • an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H+
    This reaction proceeds in the forward direction.
    EC:2.7.1.138 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Lipid metabolism; glycerolipid metabolism.

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrial intermembrane space
Molecular Functionacylglycerol kinase activity
Molecular FunctionATP-dependent diacylglycerol kinase activity
Molecular Functionceramide kinase activity
Molecular FunctionD-erythro-sphingosine kinase activity
Biological Processceramide biosynthetic process
Biological Processglycerolipid metabolic process
Biological Processphosphorylation
Biological Processsphingosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acylglycerol kinase, mitochondrial
  • EC number
  • Alternative names
    • Multiple substrate lipid kinase

Gene names

    • Name
      Agk
    • ORF names
      g.42111

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Sternorrhyncha > Aphidomorpha > Aphidoidea > Aphididae > Sipha

Accessions

  • Primary accession
    A0A2S2QPA9

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-136DAGKc

Sequence similarities

Belongs to the AGK family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    410
  • Mass (Da)
    46,213
  • Last updated
    2018-07-18 v1
  • MD5 Checksum
    AE71255E3E14E5C1A8BADC34BF42F2B4
MFMSKCCRTVSAYGDMSLSVDKKPKKVTVILNPAANKRNAKSDFEKYCAPLLHLAGYSVTVLTTEREGGARTLVENLIGETDALIVAGGDGTLSEVVTGLLRRLKGDTSLTEHLPIGILPLGRTNNVAHRLLQPQDNNRVHFLANATMTIINEVNSAYPVVKIENLQSKNPEKCVYALNNIEWGSMREVKVARDHYWYFGKLRDFAAYVFGNSLLNYTIYAELEYSPPCSGCSNCYIKKSNESSNLFSWLSWAFSFKKNPGGIDYSKIINPDCNSYTNASIKTSNVNINLDTEQTPVLKINLGPENITYSEFIKEGYSKLRDEPSKIQNSIIEAKSITIRPQNEDEDKWLSIDNEDYEVKPMKLSLLPNAVYLFKPDNRTNQNQSQTKEDQGPRLFLDKFNKHVGMKQFV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GGMS01010406
EMBL· GenBank· DDBJ
MBY79609.1
EMBL· GenBank· DDBJ
Transcribed RNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help