A0A2S2QNI1 · A0A2S2QNI1_9HEMI

Function

Catalytic activity

  • heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:7.6.2.5 (UniProtKB | ENZYME | Rhea)
  • pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentearly endosome membrane
Cellular Componentextracellular region
Cellular ComponentGolgi membrane
Cellular Componentlysosomal membrane
Cellular Componentmelanosome membrane
Cellular Componentmitochondrial outer membrane
Cellular Componentmultivesicular body membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionheme binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-binding cassette sub-family B member 6
  • EC number
  • Alternative names
    • ABC-type heme transporter ABCB6

Gene names

    • Name
      abcb6_0
    • Synonyms
      LOC112684759
    • ORF names
      g.32131

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Sternorrhyncha > Aphidomorpha > Aphidoidea > Aphididae > Sipha

Accessions

  • Primary accession
    A0A2S2QNI1

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Early endosome membrane
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Golgi apparatus membrane
; Multi-pass membrane protein
Late endosome membrane
Lysosome membrane
Melanosome membrane
Mitochondrion outer membrane
; Multi-pass membrane protein
Secreted, extracellular exosome

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane26-46Helical
Transmembrane67-88Helical
Transmembrane94-112Helical
Transmembrane133-151Helical
Transmembrane171-189Helical
Transmembrane246-267Helical
Transmembrane287-306Helical
Transmembrane363-385Helical
Transmembrane391-412Helical
Transmembrane479-501Helical
Transmembrane513-535Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain252-537ABC transmembrane type-1
Domain571-805ABC transporter
Region809-838Disordered
Compositional bias815-831Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    838
  • Mass (Da)
    95,238
  • Last updated
    2018-07-18 v1
  • MD5 Checksum
    E00CFC07C7E2850B3EF0974EA52F1DC7
MFCPNGSFIDLWSDVKTSECFVDTTIASILAVFMIFFGTAQCSIYGKYSTPLSQAAIPQSRLYYVQMIITFIFPLLAVAKFFVDIYLFQSGVAYGYQSLYMLTMVFVFPLSAKLVLMERNSLLPSMPARGHGLVLLIFWILVFVAQNVNVLIVKKEDWWIQLQNINGQIEFGIFVANYILSFLLLILGLKAPGIMTARDYLSLHNSTDLFLDSDRVEEVSTWDNVVRKVKLIAPFLWPKNSLALQFRVVCCILLVIAGRVANVYVPLYSAKIVDSLTAVPLVFRWDLILIYIGFKFLQGGLGMGFLNNLRSFLWIRVQQYTKREVEISLFRHLHNLSLKWHLGRKTGEVLRIMDRGTDSTNSLLSFILFNIGPTIIDILVAVIFFLSYFNWMMGTVVFITMVLYIALTIIITEWRTKFQRRMNVADNSMKARSVDSMLNFETVKYYGAEEYEVQAYKEAIMIYQNEEFKTQLSLAMLNTVQNIIVCTGLLAGSLLSVHFVIDDKALTVGDYVLFTVYIIQLYGPLNYFGTFYRAIQKNFIDMENMFDLMNIKPEITDAPNAKELELKNGQVEFRNVTFSYQPERLVLQNISFVVPPGKTLALVGPSGSGKTTIVRLLFRFYDVDSGSIIIDDQNIQLVTQTSLRKAIGVVPQDTVLFNNSIKFNINYGKVEANDSEIMNSAMAAEIHDRIMKFPDLYDTQVGERGLKLSGGEKQRVAIARTILKAPAIVLLDEATSALDTKTERQIQAALDQVCNNRTTIIVAHRLSTVIHADEILVLKDGEIYERGRHDDLIIRNGLYADMWSEQRKSANDVPTHDDQSNLSNPNDTITKSYHHPHV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias815-831Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GGMS01010113
EMBL· GenBank· DDBJ
MBY79316.1
EMBL· GenBank· DDBJ
Transcribed RNA

Genome annotation databases

Similar Proteins

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