A0A2S2CUL8 · A0A2S2CUL8_9PROT
- ProteinPQQ-dependent dehydrogenase, methanol/ethanol family
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids628 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 Ca2+ ion per subunit.
Note: Binds 1 PQQ group per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 99 | pyrroloquinoline quinone (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 149 | pyrroloquinoline quinone (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 193 | pyrroloquinoline quinone (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 217 | Ca2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 302 | Ca2+ (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Active site | 345 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 345 | Ca2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 453-454 | pyrroloquinoline quinone (UniProtKB | ChEBI) | ||||
Sequence: NW |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | outer membrane-bounded periplasmic space | |
Molecular Function | calcium ion binding | |
Molecular Function | oxidoreductase activity, acting on CH-OH group of donors |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Azospirillaceae > Azospirillum
Accessions
- Primary accessionA0A2S2CUL8
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-38 | |||||
Sequence: MTLSSNTTRRRPRAAHGLGLAAAVAALLALVPPGAATA | ||||||
Chain | PRO_5015534873 | 39-628 | ||||
Sequence: GPVTWDDIAGDARTTRDVLMYGMGVEGKRYSPLAQINAETVSRLVPAWSFSFGDEKQRGQETQALVHDGVIYVTASYSRMFALDAKTGKRLWSYAHRLPDDIRPCCDVVNRGAAIYGDKVFFGTLDASIVALNKDTGKVVWKKKFADHKVGYTMTGAPTVVRDQKTGKVLLIHGSSGDEFGVVGRLFARDPETGEEVWMRPLVEGHMGRLDGKDSTPTGNPQAPSWPRGKDGQLVEAWSHGGGAPWQSATFDVETNTIVIGTGNPAPWNGWARWPGDSLYTSGQAYVDPGTGELKGFYQHTPNDAWDFSGNNELVLFDYTDANGKTVKATAHADRNGFFYVTDRVKLATAGGEPNKPNSVLAAWPFVDGITWAKGIDLKTGRPIEVEGQRPPLPAEGEKRGKPVEVSPPFLGGKNWNPMSYSEDTRLFYIAANHWKEDYWTEHVGYNPGSAYLGMGFRIHKMFDDHVGVLRALDPGTGKIVWEHKEELPLWAGTLATAGNLVFTGTGDGFVKAFNARTGEELWKFQTGSGIVSSPVTWELDGVQYVGITTGYGGAVPLWGGDLADLTTRVTQGGSFWVFKLADVKVSSAK | ||||||
Disulfide bond | 143↔144 | |||||
Sequence: CC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 247-268 | Disordered | ||||
Sequence: RLDGKDSTPTGNPQAPSWPRGK | ||||||
Region | 422-444 | Disordered | ||||
Sequence: IEVEGQRPPLPAEGEKRGKPVEV |
Sequence similarities
Belongs to the bacterial PQQ dehydrogenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length628
- Mass (Da)68,104
- Last updated2018-07-18 v1
- ChecksumB168BA6945E1554B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP029354 EMBL· GenBank· DDBJ | AWK88191.1 EMBL· GenBank· DDBJ | Genomic DNA |