A0A2S0NJE3 · A0A2S0NJE3_9MOLU

Function

function

Catalyzes the conversion of lactate to pyruvate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.

Features

Showing features for binding site, active site.

131850100150200250300
Type
IDPosition(s)Description
Binding site12-17NAD+ (UniProtKB | ChEBI)
Binding site16NAD+ (UniProtKB | ChEBI)
Binding site37NAD+ (UniProtKB | ChEBI)
Binding site69NAD+ (UniProtKB | ChEBI)
Binding site86substrate
Binding site92substrate
Binding site99NAD+ (UniProtKB | ChEBI)
Binding site105NAD+ (UniProtKB | ChEBI)
Binding site122-124NAD+ (UniProtKB | ChEBI)
Binding site124-127substrate
Binding site147NAD+ (UniProtKB | ChEBI)
Binding site152-155substrate
Active site179Proton acceptor
Binding site232substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-lactate dehydrogenase activity
Biological Processglycolytic process
Biological Processlactate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    L-lactate dehydrogenase
  • EC number
  • Short names
    L-LDH

Gene names

    • Name
      ldh
    • ORF names
      C5T88_00790

Organism names

Accessions

  • Primary accession
    A0A2S0NJE3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, modified residue.

Type
IDPosition(s)Description
Signal1-23
ChainPRO_501573914324-318L-lactate dehydrogenase
Modified residue223Phosphotyrosine

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-146Lactate/malate dehydrogenase N-terminal
Domain149-314Lactate/malate dehydrogenase C-terminal

Sequence similarities

Belongs to the LDH/MDH superfamily. LDH family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    318
  • Mass (Da)
    34,144
  • Last updated
    2018-07-18 v1
  • Checksum
    9190F4DBDB56FE80
MKKTPNKVVLIGAGAVGTSFLYAAINQGLASDYVLIDAFPQAAEGNAIDLSDTMSVLPFPATTIKAGDYADCKDADIIVITAGRPQKPGETRLDMVAGNAVIMKTIAEEILKSGFDGITIIASNPVDVLTSVYQEVTGFDQNKVIGSGTTLDSARLKRLIADKLNVGAQSVDAYLAGEHGDSAVAVWSHAVVMGQPISKYIKDGKITQKELDEIRDQAVHMGYKIIELKRATFYGIGAVLTRMCRVILRDEKEALMVGAKLNGEYHNDDVYTGVPAIIGANGIEQIIEWKLTQVEQKQFDASVATLKATLVKAREAIK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP027019
EMBL· GenBank· DDBJ
AVP49122.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help