A0A2R9BCI1 · A0A2R9BCI1_PANPA
- ProteinParaoxonase
- GenePON1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids354 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- a phenyl acetate + H2O = a phenol + acetate + H+
Cofactor
Note: Binds 2 calcium ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 53 | Ca2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 54 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Active site | 115 | Proton acceptor | |||
Binding site | 117 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 168 | Ca2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 169 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 224 | Ca2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 269 | Ca2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 270 | Ca2+ 1 (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | spherical high-density lipoprotein particle | |
Molecular Function | acyl-L-homoserine-lactone lactonohydrolase activity | |
Molecular Function | aryldialkylphosphatase activity | |
Molecular Function | arylesterase activity | |
Molecular Function | calcium ion binding | |
Molecular Function | phospholipid binding | |
Molecular Function | protein homodimerization activity | |
Biological Process | carboxylic acid catabolic process | |
Biological Process | cholesterol metabolic process | |
Biological Process | lactone catabolic process | |
Biological Process | organophosphate catabolic process | |
Biological Process | phosphatidylcholine metabolic process | |
Biological Process | positive regulation of cholesterol efflux | |
Biological Process | response to toxic substance |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameParaoxonase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan
Accessions
- Primary accessionA0A2R9BCI1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, disulfide bond, glycosylation.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-15 | ||||
Chain | PRO_5015340315 | 16-354 | Paraoxonase | ||
Disulfide bond | 42↔352 | In form B | |||
Glycosylation | 253 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 270 | N-linked (GlcNAc...) asparagine | |||
Glycosylation | 323 | N-linked (GlcNAc...) asparagine | |||
Post-translational modification
Glycosylated.
Keywords
- PTM
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length354
- Mass (Da)39,638
- Last updated2018-06-20 v1
- MD5 ChecksumA8E5DC4793141E63FB43B67D813C404A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJFE02030127 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |