A0A2R9B656 · A0A2R9B656_PANPA
- ProteinSuccinate-semialdehyde dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids535 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Catalytic activity
- succinate semialdehyde + NAD+ + H2O = succinate + NADH + 2 H+
Pathway
Amino-acid degradation; 4-aminobutanoate degradation.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 306 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | succinate-semialdehyde dehydrogenase (NAD+) activity | |
Biological Process | gamma-aminobutyric acid catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate-semialdehyde dehydrogenase
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan
Accessions
- Primary accessionA0A2R9B656
Proteomes
Subcellular Location
Expression
Gene expression databases
Interaction
Subunit
Homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length535
- Mass (Da)57,088
- Last updated2018-06-20 v1
- ChecksumA9B82F5F25139AF7
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2R9B9W2 | A0A2R9B9W2_PANPA | 507 | |||
A0A2R9B7N8 | A0A2R9B7N8_PANPA | 441 | |||
A0A2R9B652 | A0A2R9B652_PANPA | 548 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJFE02081263 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJFE02081264 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJFE02081265 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJFE02081266 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJFE02081267 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |