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A0A2R9APK7 · A0A2R9APK7_PANPA

Function

Catalytic activity

Pathway

Steroid metabolism.

Features

Showing features for active site, site, binding site.

Type
IDPosition(s)Description
Active site55Proton donor
Site84Lowers pKa of active site Tyr
Binding site117substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionaldose reductase (NADPH) activity
Molecular Functionandrosterone dehydrogenase (B-specific) activity
Molecular Functionbile acid binding
Molecular Functionestradiol 17-beta-dehydrogenase [NAD(P)+] activity
Molecular Functionketosteroid monooxygenase activity
Molecular Functionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Molecular Functiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Biological Processbile acid metabolic process
Biological Processcellular response to jasmonic acid stimulus
Biological Processdaunorubicin metabolic process
Biological Processdigestion
Biological Processdoxorubicin metabolic process
Biological Processepithelial cell differentiation
Biological Processpositive regulation of reactive oxygen species metabolic process
Biological Processprogesterone metabolic process
Biological Processprostaglandin metabolic process
Biological Processresponse to organophosphorus
Biological Processretinal metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Aldo-keto reductase family 1 member C1

Gene names

    • Name
      AKR1C1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan

Accessions

  • Primary accession
    A0A2R9APK7

Proteomes

Subcellular Location

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-283NADP-dependent oxidoreductase

Sequence similarities

Belongs to the aldo/keto reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    295
  • Mass (Da)
    33,566
  • Last updated
    2018-06-20 v1
  • MD5 Checksum
    095D18841F75FEFAD88DF96602732B83
MDSKYQCVKLNDGHFMPVLGFGTYAPPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEELIPKDEVGKVLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNMQFAGPPNYPFSDEY

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2R9AVW5A0A2R9AVW5_PANPAAKR1C1205

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJFE02097782
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AJFE02097783
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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