A0A2R9APK7 · A0A2R9APK7_PANPA
- ProteinAldo-keto reductase family 1 member C1
- GeneAKR1C1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids295 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP+ = catechol + NADPH + H+
- (20S)-hydroxypregn-4-en-3-one + NAD+ = progesterone + NADH + H+This reaction proceeds in the forward and the backward directions.
- (20S)-hydroxypregn-4-en-3-one + NADP+ = progesterone + NADPH + H+This reaction proceeds in the forward and the backward directions.
Pathway
Steroid metabolism.
Features
Showing features for active site, site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 55 | Proton donor | |||
Site | 84 | Lowers pKa of active site Tyr | |||
Binding site | 117 | substrate | |||
GO annotations
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan
Accessions
- Primary accessionA0A2R9APK7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length295
- Mass (Da)33,566
- Last updated2018-06-20 v1
- MD5 Checksum095D18841F75FEFAD88DF96602732B83
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2R9AVW5 | A0A2R9AVW5_PANPA | AKR1C1 | 205 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJFE02097782 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJFE02097783 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |