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A0A2R9ABJ2 · A0A2R9ABJ2_PANPA

Function

Catalytic activity

Features

Showing features for active site, site, binding site.

Type
IDPosition(s)Description
Active site50Proton donor
Site80Lowers pKa of active site Tyr
Binding site113substrate

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcytosol
Cellular Componentsynapse
Molecular Functionaldose reductase (NADPH) activity
Molecular Functionallyl-alcohol dehydrogenase activity
Molecular Functionglucuronolactone reductase activity
Molecular FunctionL-glucuronate reductase activity
Molecular FunctionS-nitrosoglutathione reductase (NADH) activity
Biological Processaldehyde catabolic process
Biological Processcellular detoxification of aldehyde
Biological ProcessD-glucuronate catabolic process to D-xylulose 5-phosphate
Biological Processdaunorubicin metabolic process
Biological Processdoxorubicin metabolic process
Biological ProcessL-ascorbic acid biosynthetic process

Keywords

  • Ligand
    • #NADP

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aldo-keto reductase family 1 member A1
  • EC number
  • Alternative names
    • Alcohol dehydrogenase [NADP(+)]
    • Aldehyde reductase
    • Glucuronate reductase
    • Glucuronolactone reductase
    • S-nitroso-CoA reductase

Gene names

    • Name
      AKR1A1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan

Accessions

  • Primary accession
    A0A2R9ABJ2

Proteomes

Subcellular Location

Keywords

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain17-293NADP-dependent oxidoreductase

Sequence similarities

Belongs to the aldo/keto reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    325
  • Mass (Da)
    36,573
  • Last updated
    2018-06-20 v1
  • MD5 Checksum
    C691DE80A621574E3C7ADBC886609354
MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJFE02040748
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AJFE02040749
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AJFE02040750
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AJFE02040751
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AJFE02040752
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AJFE02040753
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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