A0A2R8YFV2 · A0A2R8YFV2_HUMAN

  • Protein
    WIZ zinc finger
  • Gene
    WIZ
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmidbody
Cellular Componentnucleoplasm

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • WIZ zinc finger

Gene names

    • Name
      WIZ

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A2R8YFV2

Proteomes

Organism-specific databases

Subcellular Location

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 1,809 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)1016PRIDEPhosphoserine
Modified residue (large scale data)1030PRIDEPhosphoserine
Modified residue (large scale data)1031PRIDEPhosphoserine
Modified residue (large scale data)1037PRIDEPhosphothreonine
Modified residue (large scale data)1044PRIDEPhosphoserine
Modified residue (large scale data)1046PRIDEPhosphothreonine
Modified residue (large scale data)1054PRIDEPhosphoserine
Modified residue (large scale data)1058PRIDEPhosphoserine
Modified residue (large scale data)1060PRIDEPhosphoserine
Modified residue (large scale data)1065PRIDEPhosphoserine
Modified residue (large scale data)1073PRIDEPhosphoserine
Modified residue (large scale data)1127PRIDEPhosphoserine
Modified residue (large scale data)1154PRIDEPhosphoserine
Modified residue (large scale data)1169PRIDEPhosphoserine
Modified residue (large scale data)1170PRIDEPhosphoserine
Modified residue (large scale data)1175PRIDEPhosphoserine
Modified residue (large scale data)1177PRIDEPhosphoserine
Modified residue (large scale data)1182PRIDEPhosphoserine
Modified residue (large scale data)1194PRIDEPhosphoserine
Modified residue (large scale data)1199PRIDEPhosphoserine
Modified residue (large scale data)1201PRIDEPhosphothreonine
Modified residue (large scale data)1203PRIDEPhosphoserine
Modified residue (large scale data)1266PRIDEPhosphoserine
Modified residue (large scale data)1311PRIDEPhosphoserine
Modified residue (large scale data)1357PRIDEPhosphoserine
Modified residue (large scale data)1362PRIDEPhosphoserine
Modified residue (large scale data)1383PRIDEPhosphoserine
Modified residue (large scale data)1385PRIDEPhosphothreonine
Modified residue (large scale data)1400PRIDEPhosphoserine
Modified residue (large scale data)1528PRIDEPhosphoserine
Modified residue (large scale data)1565PRIDEPhosphoserine
Modified residue (large scale data)1677PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-77Disordered
Domain315-337C2H2-type
Domain352-379C2H2-type
Region424-447Disordered
Region594-626Disordered
Domain817-839C2H2-type
Region867-891Disordered
Domain918-940C2H2-type
Region1020-1086Disordered
Compositional bias1049-1067Polar residues
Domain1091-1118C2H2-type
Region1139-1222Disordered
Compositional bias1185-1202Pro residues
Domain1275-1302C2H2-type
Region1331-1379Disordered
Compositional bias1351-1365Pro residues
Domain1445-1467C2H2-type
Region1511-1602Disordered
Compositional bias1575-1591Basic and acidic residues
Region1677-1699Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,699
  • Mass (Da)
    183,745
  • Last updated
    2018-06-20 v1
  • Checksum
    93688CB1B8FBE529
MEGSLAGSLAAPDRPQGPERLPGPAPRENIEGGAEAAEGEGGIFRSTRYLPVTKEGPRDILDGRGGISDGQPHPGLSEALPRVTSATHRISSCCWDGGSLDFRPGSPPPHLLGHFPGTPDGRGPWEHPLVQEAGEGILSERRFEDSVIVRTMKPHAELEGSRRFLHHRGEPRLLEKHAQGRPRFDWLQDEDEQGSPQDAGLHLDLPAQPPPLAPFRRVFVPVEDTPKTLDMAVVGGREDLEDLEGLAQPSEWGLPTSASEVATQTWTVNSEASVERLQPLLPPIRTGPYLCELLEEVAEGVASPDEDEDEEPAVFPCIECSIYFKQKEHLLEHMSQHRRAPGQEPPADLAPLACGECGWAFADPTALEQHRQLHQASREKIIEEIQKLKQVPGDEGREARLQCPKCVFGTNSSRAYVQHAKLHMREPPGQTTKEPFGGSSGAGSPSPEASALLYQPYGAAVGLSACVFCGFPAPSESLLREHVRLVHAHPHWEEDGEAYEEDPASQPGTSQDAHACFPDTAVDYFGKAEPSLAPMWRENPAGYDPSLAFGPGCQQLSIRDFPLSKPLLHGTGQRPLGRLAFPSTLASTPYSLQLGRNKSTVHPQGLGERRRPWSEEEEEEEEEEDVVLTSEMDFSPENGVFSPLATPSLIPQAALELKQAFREALQAVEATQGQQQQLRGMVPIVLVAKLGPQVMAAARVPPRLQPEELGLAGAHPLDFLLLDAPLGGPLGLDTLLDGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAEQPPSPLGREPGGPPGSFLTSRRPRLPLTVPFPPTWAEDPGPAYGDAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAHLGLPPGLAKKSSSLKEVVAGAPRPGLLSLAKPLDAPAVNKAIKSPPGFSAKGLGHPPSSPLLKKTPLALAGSPTPKNPEDKSPQLSLSPRPASPKAQWPQSEDEGPLNLTSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPPGPSPKALAKMMGGAGPGSSLEARSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFPGLAAPSLPKKLKPEQIRVEIKREMLPGALHGELHPSEGPWGAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALAEDGPPTVAPGPVQSPLPLSPLAGRPGKPGAGPAQVPRELSLTPITGAKPSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKVGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPSLGLAPGGLAVVGRSAGGEPGPEAGRAADGGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGGEDTNDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEESQAPQAQTAAAEAP

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
O95785WIZ_HUMANWIZ1651
M0QXA7M0QXA7_HUMANWIZ968
M0QXF8M0QXF8_HUMANWIZ133
A0A3B3IS05A0A3B3IS05_HUMANWIZ96
A0A669KBG4A0A669KBG4_HUMANWIZ933
A0A669KBH9A0A669KBH9_HUMANWIZ1066
A0A669KAV7A0A669KAV7_HUMANWIZ1889
B9EGQ5B9EGQ5_HUMANWIZ832

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1049-1067Polar residues
Compositional bias1185-1202Pro residues
Compositional bias1351-1365Pro residues
Compositional bias1575-1591Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC006128
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC007059
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC011492
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp