A0A2R8YEJ5 · A0A2R8YEJ5_HUMAN
- ProteinLeucine rich repeats and guanylate kinase domain containing
- GeneLRGUK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1130 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionA0A2R8YEJ5
Proteomes
Organism-specific databases
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,248 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 73-96 | Disordered | ||||
Sequence: DSDGDEDQGEGEAGSEESSESEML | ||||||
Compositional bias | 75-96 | Acidic residues | ||||
Sequence: DGDEDQGEGEAGSEESSESEML | ||||||
Domain | 414-597 | Guanylate kinase-like | ||||
Sequence: YPMLILAGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQDVFDEMVNMGKFILTFSYGNHKYGLNRDTVEGIARDGLASCIHMEIEGVRSLKYSYFEPRYILVVPMNKEKYEGYLRRKGLFSRAEIEFAVSRVDLYIKINQNFPGYFDEVINADDLDVAYQKLSQLIR | ||||||
Region | 673-698 | Disordered | ||||
Sequence: LAQDGETHQKELSPDSHLNPELPQHL | ||||||
Region | 737-1130 | Disordered | ||||
Sequence: VPEVEASEVGQSPITPTLVPPVHPSPPSSRSPQPGQDKESGEAQVTPTGPPLSEPLQGPGPTPLSPQRIQDEEIESDKLPPSSSHHDPPKDSSHTDLVQKLAGDSQQALKEETSKPEAIRVSIPHPELPHPQDLATDTKQPQARGAPGTLLPRSRLAPTRLPQPQVLAPLQSRRPTPKLLSPSREEALGTTSHQTMTVSPRLPPTREADTSKLPPISPPHSKPPPNLSPQAAHSLQQVQEEKVSEVKLPLISPPSQEQAEPRILSPAQEEAAQKVRLPRIPAPLPEPGLPQNSGTQPDPRPAKERKAPQAGSSSRRKIPDMRASPHNQGPLQQTGAREKKLPNQKGTARGLAPLEEAPPGNHQPALQLEPHDQPAPTMVPDDPNPSPPLVSCLS | ||||||
Compositional bias | 753-767 | Pro residues | ||||
Sequence: TLVPPVHPSPPSSRS | ||||||
Compositional bias | 768-787 | Polar residues | ||||
Sequence: PQPGQDKESGEAQVTPTGPP | ||||||
Compositional bias | 806-830 | Basic and acidic residues | ||||
Sequence: QDEEIESDKLPPSSSHHDPPKDSSH | ||||||
Compositional bias | 921-937 | Polar residues | ||||
Sequence: EEALGTTSHQTMTVSPR | ||||||
Compositional bias | 963-977 | Polar residues | ||||
Sequence: LSPQAAHSLQQVQEE | ||||||
Compositional bias | 1016-1030 | Pro residues | ||||
Sequence: IPAPLPEPGLPQNSG | ||||||
Compositional bias | 1062-1076 | Polar residues | ||||
Sequence: HNQGPLQQTGAREKK |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,130
- Mass (Da)124,833
- Last updated2018-06-20 v1
- Checksum42A99BE5A497344E
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q96M69 | LRGUK_HUMAN | LRGUK | 825 | ||
A0A8Q3SIT3 | A0A8Q3SIT3_HUMAN | LRGUK | 56 | ||
A0A8Q3SI13 | A0A8Q3SI13_HUMAN | LRGUK | 1131 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 75-96 | Acidic residues | ||||
Sequence: DGDEDQGEGEAGSEESSESEML | ||||||
Compositional bias | 753-767 | Pro residues | ||||
Sequence: TLVPPVHPSPPSSRS | ||||||
Compositional bias | 768-787 | Polar residues | ||||
Sequence: PQPGQDKESGEAQVTPTGPP | ||||||
Compositional bias | 806-830 | Basic and acidic residues | ||||
Sequence: QDEEIESDKLPPSSSHHDPPKDSSH | ||||||
Compositional bias | 921-937 | Polar residues | ||||
Sequence: EEALGTTSHQTMTVSPR | ||||||
Compositional bias | 963-977 | Polar residues | ||||
Sequence: LSPQAAHSLQQVQEE | ||||||
Compositional bias | 1016-1030 | Pro residues | ||||
Sequence: IPAPLPEPGLPQNSG | ||||||
Compositional bias | 1062-1076 | Polar residues | ||||
Sequence: HNQGPLQQTGAREKK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC008154 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC018646 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF510982 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |