A0A2R8YD28 · A0A2R8YD28_HUMAN

  • Protein
    Cyclin dependent kinase 13
  • Gene
    CDK13
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Features

Showing features for binding site.

145650100150200250300350400450
TypeIDPosition(s)Description
Binding site252ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Cyclin dependent kinase 13

Gene names

    • Name
      CDK13

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A2R8YD28

Proteomes

Organism-specific databases

Disease & Variants

Variants

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The viewer provides 442 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)8PRIDEPhosphoserine
Modified residue (large scale data)11PRIDEPhosphoserine
Modified residue (large scale data)12PRIDEPhosphothreonine
Modified residue (large scale data)14PRIDEPhosphothreonine
Modified residue (large scale data)18PRIDEPhosphothreonine
Modified residue (large scale data)23PRIDEPhosphoserine
Modified residue (large scale data)25PRIDEPhosphoserine
Modified residue (large scale data)43PRIDEPhosphoserine
Modified residue (large scale data)45PRIDEPhosphoserine
Modified residue (large scale data)46PRIDEPhosphoserine
Modified residue (large scale data)106PRIDEPhosphothreonine
Modified residue (large scale data)108PRIDEPhosphoserine
Modified residue (large scale data)180PRIDEPhosphoserine
Modified residue (large scale data)182PRIDEPhosphoserine
Modified residue (large scale data)382PRIDEPhosphoserine
Modified residue (large scale data)385PRIDEPhosphoserine
Modified residue (large scale data)389PRIDEPhosphothreonine

Proteomic databases

Expression

Gene expression databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY A0A2R8YD28TRIM7 Q9C0293EBI-22523896, EBI-2813981

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-29Polar residues
Region1-62Disordered
Region86-139Disordered
Compositional bias87-110Basic and acidic residues
Region172-191Disordered
Domain223-456Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    456
  • Mass (Da)
    51,143
  • Last updated
    2018-06-20 v1
  • Checksum
    CCD084F2567CBDFD
XAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q14004CDK13_HUMANCDK131512
A0A2R8Y7W5A0A2R8Y7W5_HUMANCDK131099
A0A2R8Y7Y0A0A2R8Y7Y0_HUMANCDK13257
A0A2R8Y644A0A2R8Y644_HUMANCDK13239
A0A2R8Y4Z0A0A2R8Y4Z0_HUMANCDK131308
A0A2R8YEB7A0A2R8YEB7_HUMANCDK13143
A0A2R8YCQ1A0A2R8YCQ1_HUMANCDK13288
A0A2R8YFE7A0A2R8YFE7_HUMANCDK13279
A0A2R8YF61A0A2R8YF61_HUMANCDK13915

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias1-29Polar residues
Compositional bias87-110Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC006023
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC072061
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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