A0A2R8Y857 · A0A2R8Y857_HUMAN
- ProteinTreacle ribosome biogenesis factor 1
- GeneTCOF1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids297 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionA0A2R8Y857
Proteomes
Organism-specific databases
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 280 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 83 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 84 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 85 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 87 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 88 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 107 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 110 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 111 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 119 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 120 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 147 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 153 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 156 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 160 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 164 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 167 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 168 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 171 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 173 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 178 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 220 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 221 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 227 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 233 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 271 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 57-74 | Basic and acidic residues | ||||
Sequence: SELGRKRKAEEDAALQAK | ||||||
Region | 57-297 | Disordered | ||||
Sequence: SELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKE | ||||||
Compositional bias | 102-116 | Polar residues | ||||
Sequence: TPRLASTNSSVLGAD | ||||||
Compositional bias | 140-174 | Polar residues | ||||
Sequence: PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETE | ||||||
Domain | 195-277 | Treacle protein | ||||
Sequence: QADSSSEDTSSSSDETDVEAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA | ||||||
Domain | 259-296 | Treacle protein | ||||
Sequence: EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length297
- Mass (Da)30,909
- Last updated2018-06-20 v1
- ChecksumD01A7EFFA9FE3AAD
Computationally mapped potential isoform sequences
There are 8 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q13428 | TCOF_HUMAN | TCOF1 | 1488 | ||
A0A2R8Y4M7 | A0A2R8Y4M7_HUMAN | TCOF1 | 108 | ||
E7ETY2 | E7ETY2_HUMAN | TCOF1 | 1488 | ||
H0YA99 | H0YA99_HUMAN | TCOF1 | 188 | ||
H0YAB7 | H0YAB7_HUMAN | TCOF1 | 148 | ||
H0Y8Y7 | H0Y8Y7_HUMAN | TCOF1 | 994 | ||
A0A6I8PRA0 | A0A6I8PRA0_HUMAN | TCOF1 | 1240 | ||
A0A3B3IS06 | A0A3B3IS06_HUMAN | TCOF1 | 1358 |
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 57-74 | Basic and acidic residues | ||||
Sequence: SELGRKRKAEEDAALQAK | ||||||
Compositional bias | 102-116 | Polar residues | ||||
Sequence: TPRLASTNSSVLGAD | ||||||
Compositional bias | 140-174 | Polar residues | ||||
Sequence: PHPATGKTVANLLSGKSPRKSAEPSANTTLVSETE | ||||||
Non-terminal residue | 297 | |||||
Sequence: E |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC011372 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |