Regulation of CNKSR2 protein stability by the HECT E3 ubiquitin ligase Smurf2, and its role in breast cancer progression.David D., Surendran A., Thulaseedharan J.V., Nair A.S.View abstractAnnotationHigh CNKSR2 expression is associated with breast cancer progression.CategoryInteractionSourceGeneRif: 22866PubMedEurope PMCBMC Cancer 18:284-284 (2018)Mapped to10
CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.Rajakulendran T., Sahmi M., Kurinov I., Tyers M., Therrien M., Sicheri F.View abstractAnnotationCNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.CategoriesInteraction, StructureSourceGeneRif: 22866PubMedEurope PMCProc Natl Acad Sci U S A 105:2836-2841 (2008)Mapped to8
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf.Lanigan T.M., Liu A., Huang Y.Z., Mei L., Margolis B., Guan K.-L.View abstractAnnotationCNK2 through interaction with Raf and Rlf may function as a regulator of Ras signaling.CategoriesInteraction, Subcellular LocationSourceGeneRif: 22866PubMedEurope PMCFASEB J. 17:2048-2060 (2003)Cited in1Mapped to6