No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.Tang Y., Wu J., Sun X., Tan S., Li W., Yin S., Liu L., Chen Y., Liu Y.[...], Cai J.View abstractSourceMGI: 1916396PubMedEurope PMCCell Rep 43:114237-114237 (2024)Mapped to4
LRRK2 G2019S Promotes Colon Cancer Potentially via LRRK2-GSDMD Axis- Mediated Gut Inflammation.Wang Y., Gao J.Z., Sakaguchi T., Maretzky T., Gurung P., Narayanan N.S., Short S., Xiong Y., Kang Z.View abstractSourceMGI: 1916396PubMedEurope PMCCells 13:565-565 (2024)Mapped to7
Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation.Speaks S., McFadden M.I., Zani A., Solstad A., Leumi S., Roettger J.E., Kenney A.D., Bone H., Zhang L.[...], Yount J.S.View abstractSourceMGI: 1916396PubMedEurope PMCNat Commun 15:2751-2751 (2024)Mapped to4
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8pisup>+pi/sup> T cell effector functions.Cong J., Liu P., Han Z., Ying W., Li C., Yang Y., Wang S., Yang J., Cao F.[...], Zhu S.View abstractSourceMGI: 1916396PubMedEurope PMCImmunity 57:876-889.e11 (2024)Mapped to27
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-beta deposition in Alzheimer's disease.Daily K.P., Badr A., Eltobgy M., Estfanous S., Whitham O., Tan M.H., Carafice C., Krause K., McNamara A.[...], Amer A.O.View abstractSourceMGI: 1916396PubMedEurope PMCAlzheimers Res Ther 16:29-29 (2024)Mapped to26
Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbalpha-C/EBPbeta- SAA1 axis.Shim D.W., Eo J.C., Kim S., Hwang I., Nam B., Shin J.E., Han S.H., Yu J.W.View abstractSourceMGI: 1916396PubMedEurope PMCExp Mol Med 56:370-382 (2024)Mapped to10
Gasdermin E dictates inflammatory responses by controlling the mode of neutrophil death.Ma F., Ghimire L., Ren Q., Fan Y., Chen T., Balasubramanian A., Hsu A., Liu F., Yu H.[...], Luo H.R.View abstractSourceMGI: 1916396PubMedEurope PMCNat Commun 15:386-386 (2024)Mapped to11
Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice.Fattinger S.A., Maurer L., Geiser P., Bernard E.M., Enz U., Ganguillet S., Guel E., Kroon S., Demarco B.[...], Hardt W.D.View abstractSourceMGI: 1916396PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 120:e2315503120-e2315503120 (2023)Cited in1Mapped to22
PD-L1 promotes GSDMD-mediated NET release by maintaining the transcriptional activity of Stat3 in sepsis-associated encephalopathy.Zhu C.L., Xie J., Liu Q., Wang Y., Li H.R., Yu C.M., Li P., Deng X.M., Bian J.J., Wang J.F.View abstractSourceMGI: 1916396PubMedEurope PMCInt J Biol Sci 19:1413-1429 (2023)Mapped to9
GSDMD deficiency ameliorates hyperoxia-induced BPD and ROP in neonatal mice.Sonny S., Yuan H., Chen S., Duncan M.R., Chen P., Benny M., Young K., Park K.K., Schmidt A.F., Wu S.View abstractSourceMGI: 1916396PubMedEurope PMCSci Rep 13:143-143 (2023)Mapped to4
GSDMD-mediated NETosis promotes the development of acute respiratory distress syndrome.Xie J., Zhu C.L., Wan X.J., Zhao Z.Z., Meng Y., Li P., Guo Y., Liu Q., Bian J.J.[...], Wang J.F.View abstractSourceMGI: 1916396PubMedEurope PMCEur J Immunol 53:e2250011-e2250011 (2023)Mapped to5
Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis.Yuan C., Wu M., Xiao Q., Zhao W., Li H., Zhong Y., Zhao M., Li C., Li Y., Yang X.SourceMGI: 1916396PubMedEurope PMCSignal Transduct Target Ther 6:92-92 (2021)Mapped to15