A0A2R8QM71 · A0A2R8QM71_DANRE
- Proteinnon-specific serine/threonine protein kinase
- Genemink1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1273 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | actin cytoskeleton organization | |
Biological Process | MAPK cascade | |
Biological Process | neuron projection morphogenesis | |
Biological Process | regulation of MAPK cascade |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A2R8QM71
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 25-289 | Protein kinase | ||||
Sequence: FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEEEEEEIKAEINMLKKYSHHRNIATYYGAFVKKSPPGHDDQLWLVMEFCGAGSVTDLVKNTKGNSLKEDWIAYICREILRGLSHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDSTYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFIDFIEGCLVKSYPNRPSTEQLLKHSFI | ||||||
Region | 307-348 | Disordered | ||||
Sequence: DRTRKKRGEKEETEYEYSGSDEEDENRGDERESSSILNVPGE | ||||||
Region | 363-466 | Disordered | ||||
Sequence: KERSEALKRQQAQLAAQRRDPEEHKRQLLHDRQKRIEEQKEQRRRLEEQQRKEREMVRQQQDKAPHRRLDDMRREEDRRLAEREQEYKRKQLEEQRQSERLQRQ | ||||||
Compositional bias | 377-465 | Basic and acidic residues | ||||
Sequence: AAQRRDPEEHKRQLLHDRQKRIEEQKEQRRRLEEQQRKEREMVRQQQDKAPHRRLDDMRREEDRRLAEREQEYKRKQLEEQRQSERLQR | ||||||
Region | 510-559 | Disordered | ||||
Sequence: ERSKLNRQGSPKICTTVSDTNIQSRSESINQSGAAQTPPMQRPVEPQGGQ | ||||||
Compositional bias | 517-547 | Polar residues | ||||
Sequence: QGSPKICTTVSDTNIQSRSESINQSGAAQTP | ||||||
Region | 577-653 | Disordered | ||||
Sequence: VPRSQSLCDQPTKTMSAFPTQDPSPTPTPRPLHSRELVRQNSDPTSETPAPQSRPMRDDRGPWIRLPEIEQPPKIPQ | ||||||
Compositional bias | 581-597 | Polar residues | ||||
Sequence: QSLCDQPTKTMSAFPTQ | ||||||
Compositional bias | 614-628 | Polar residues | ||||
Sequence: VRQNSDPTSETPAPQ | ||||||
Region | 669-881 | Disordered | ||||
Sequence: GIRHPVRASNPDLSRNERWERGDSMSIMSNLPQTGSLERHRILSSSKMDSSPTLSHDGRHKPGESRTSSRPSRPASYKRAIGEDHGLYSKERAEEQPRPPVKANDYSSSSESSESSEESESGEGAEEESPTDRPRDADSDSVNTMVVHEEEEGEGGEEERAGGYGDQTMLVQRTPEKRSHNGYTNLPDVVQPSHSPTDSASHSSPGKDSTYDY | ||||||
Compositional bias | 694-720 | Polar residues | ||||
Sequence: SIMSNLPQTGSLERHRILSSSKMDSSP | ||||||
Compositional bias | 721-735 | Basic and acidic residues | ||||
Sequence: TLSHDGRHKPGESRT | ||||||
Compositional bias | 745-767 | Basic and acidic residues | ||||
Sequence: YKRAIGEDHGLYSKERAEEQPRP | ||||||
Compositional bias | 794-818 | Basic and acidic residues | ||||
Sequence: EEESPTDRPRDADSDSVNTMVVHEE | ||||||
Compositional bias | 840-881 | Polar residues | ||||
Sequence: QRTPEKRSHNGYTNLPDVVQPSHSPTDSASHSSPGKDSTYDY | ||||||
Domain | 960-1247 | CNH | ||||
Sequence: NSEILCAALWGVNLLVGTENGLKLLDRSGQGKVYPLINSRRFQQMDVLEGLNLLITISGKKNKVRVYYLAWLRNKILHNDPEVEKKQGWTTVGEMEGCVHYKVVKYERIKFLVIALKNAVEVYAWAPKPYHKFMAFKSFGDLPHRPVLVDLTVEEGQRLKVIYGSLAGFHAIDVDSGNNYDIYIPVHIQSQITPHAIVFLPNSDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAHICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKV |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,273
- Mass (Da)145,093
- Last updated2018-06-20 v1
- Checksum0ABD64406670788F
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9QDG2 | A0A8M9QDG2_DANRE | mink1 | 1314 | ||
A0A8M6YYZ8 | A0A8M6YYZ8_DANRE | mink1 | 1271 | ||
A0A8M6YY39 | A0A8M6YY39_DANRE | mink1 | 1302 | ||
A0A8M9PJK9 | A0A8M9PJK9_DANRE | mink1 | 1306 | ||
A0A8M9PX03 | A0A8M9PX03_DANRE | mink1 | 1278 | ||
A0A8M9Q813 | A0A8M9Q813_DANRE | mink1 | 1312 | ||
A0A8M6Z0G7 | A0A8M6Z0G7_DANRE | mink1 | 1265 | ||
A0A8M6Z686 | A0A8M6Z686_DANRE | mink1 | 1300 | ||
F1REC7 | F1REC7_DANRE | mink1 | 156 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 377-465 | Basic and acidic residues | ||||
Sequence: AAQRRDPEEHKRQLLHDRQKRIEEQKEQRRRLEEQQRKEREMVRQQQDKAPHRRLDDMRREEDRRLAEREQEYKRKQLEEQRQSERLQR | ||||||
Compositional bias | 517-547 | Polar residues | ||||
Sequence: QGSPKICTTVSDTNIQSRSESINQSGAAQTP | ||||||
Compositional bias | 581-597 | Polar residues | ||||
Sequence: QSLCDQPTKTMSAFPTQ | ||||||
Compositional bias | 614-628 | Polar residues | ||||
Sequence: VRQNSDPTSETPAPQ | ||||||
Compositional bias | 694-720 | Polar residues | ||||
Sequence: SIMSNLPQTGSLERHRILSSSKMDSSP | ||||||
Compositional bias | 721-735 | Basic and acidic residues | ||||
Sequence: TLSHDGRHKPGESRT | ||||||
Compositional bias | 745-767 | Basic and acidic residues | ||||
Sequence: YKRAIGEDHGLYSKERAEEQPRP | ||||||
Compositional bias | 794-818 | Basic and acidic residues | ||||
Sequence: EEESPTDRPRDADSDSVNTMVVHEE | ||||||
Compositional bias | 840-881 | Polar residues | ||||
Sequence: QRTPEKRSHNGYTNLPDVVQPSHSPTDSASHSSPGKDSTYDY |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX324194 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |