A0A2R6QPG8 · A0A2R6QPG8_ACTCC

Function

function

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site181D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site591D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site94ATP (UniProtKB | ChEBI)
Binding site144ATP (UniProtKB | ChEBI)
Binding site1551D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site176-187ATP (UniProtKB | ChEBI)
Binding site1871D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site202ATP (UniProtKB | ChEBI)
Binding site272Mg2+ 1 (UniProtKB | ChEBI)
Binding site287Mg2+ 2 (UniProtKB | ChEBI)
Binding site287Mg2+ 1 (UniProtKB | ChEBI)
Binding site2891D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site289Mg2+ 2 (UniProtKB | ChEBI)
Binding site2931D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functioninositol-1,3,4-trisphosphate 5-kinase activity
Molecular Functioninositol-1,3,4-trisphosphate 6-kinase activity
Molecular Functioninositol-3,4,5,6-tetrakisphosphate 1-kinase activity
Molecular Functionmagnesium ion binding
Biological Processinositol trisphosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inositol-tetrakisphosphate 1-kinase
  • EC number

Gene names

    • ORF names
      CEY00_Acc16079

Organism names

Accessions

  • Primary accession
    A0A2R6QPG8

Proteomes

Genome annotation databases

Subcellular Location

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-88Inositol-tetrakisphosphate 1-kinase N-terminal
Domain108-310Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp

Sequence similarities

Belongs to the ITPK1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    363
  • Mass (Da)
    40,916
  • Last updated
    2018-06-20 v1
  • Checksum
    6314B1468054D413
MAEPTRRVGVGYALAPKKQQSFIQVSLLNLARSRGIDLIRIDTNKPLVDQGPFDCVLHKLRGEDWKKQLEDYSAKYPNALIIDSPEAIERLHNRISMLEVVSELKIENETESFGIPKQIVIYDWDTLLDPCAWGEGLKFPVIAKPLVADGSAKSHKMSLVFNKDGLSKLKPPIVLQEFVNHGGVIFKVYVVGDYVKCVKRKSLPDVSEEKLGSLEGSLSFSQVSNITTSERNDDKYYEMMDLEDADMPPQSFITDIARGIQRVTKLHLFNFDVIRDTKIGNRYLVIDINYFPGYAKMPSYETVLTDFFWDVLNKKETALGNLQVISCEKEARKLVGNNACEGTDGPLPVSPLSREETENPIQV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NKQK01000014
EMBL· GenBank· DDBJ
PSS11800.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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