A0A2R6QE26 · BHL42_ACTCC
- ProteinTranscription factor BHLH42
- GeneBHLH42
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids689 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Transcription activator involved in the spatiotemporal regulation of anthocyanin biosynthesis specifically in the inner pericarp of red-fleshed kiwifruits (PubMed:30912865).
Functions in association with MYB123 to activate the promoters of LDOX (ANS) and F3GT1 that encode the dedicated enzymes for anthocyanin biosynthesis (PubMed:30912865).
Functions in association with MYB123 to activate the promoters of LDOX (ANS) and F3GT1 that encode the dedicated enzymes for anthocyanin biosynthesis (PubMed:30912865).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | protein dimerization activity | |
Biological Process | positive regulation of anthocyanin biosynthetic process | |
Biological Process | positive regulation of DNA-templated transcription |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTranscription factor BHLH42
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > Ericales > Actinidiaceae > Actinidia
Accessions
- Primary accessionA0A2R6QE26
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000448076 | 1-689 | Transcription factor BHLH42 | |||
Sequence: MAAPPSTRLQGMLQTAVQSVQWTYSLFWQLCPQQGILVWGDGYYNGAIKTRKTVLPIEVSAEEASLQRSQQLRELYDSLSAGESNQQTRRPCAALSPEDLTESEWFYLMCVSFSFPPGVGLPGKAYAKRQHVWLTGANEVDSKVFSRAILAKSARVQTVVCIPLLDGVVELGNTERVQEDIGFIHQVKSFFIDHHPPPPPKPALSEHSTSNLATSSVHPRFHSPPLPLTYAPLDPPLIANQIHMEEEQEQEQEEDEDDDDDDDDEEEAESDSEAHTGLNSEAQNPRVDHVARAAAEPSELMQLEMSEDIRLGSPDDGSNNMDPDFQLMVASQGGNPADQQQRVDSFRAESTRRWPLLQDPLGRSLQAPTSGGTGLEELTQDDTHYSQTVSTILQHQSNRWLESSSSSAAGCLMYSSQSSFSKWPLRPSDHHHQADATSQCLLKYILFTVPFLHSKYRDDNNSPKSATAADSASRFRKPTPQDELSANHVLAERRRREKLNERFIILRSLVPFVTKMDKASILGDTIEYVKQLRKNIQDLEARARQIEIDQRSRSSGDPQRSGAKAATDKRKLRIVEASGGAKGKAVDSVAVATPPPPAPPQPVAGVGVQVQVSIIESDALVELQCTHREGLLLDVMVVLRDHRVEVTAVQSSLTNGVFVAELRAKVKENVNGKKPSIVEVKRAIHQIIP |
Expression
Tissue specificity
Expressed in the inner pericarp of maturing fruits.
Interaction
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 192-287 | Disordered | ||||
Sequence: IDHHPPPPPKPALSEHSTSNLATSSVHPRFHSPPLPLTYAPLDPPLIANQIHMEEEQEQEQEEDEDDDDDDDDEEEAESDSEAHTGLNSEAQNPRV | ||||||
Compositional bias | 247-271 | Acidic residues | ||||
Sequence: EQEQEQEEDEDDDDDDDDEEEAESD | ||||||
Region | 458-489 | Disordered | ||||
Sequence: DDNNSPKSATAADSASRFRKPTPQDELSANHV | ||||||
Compositional bias | 461-480 | Polar residues | ||||
Sequence: NSPKSATAADSASRFRKPTP | ||||||
Region | 483-496 | Basic motif | ||||
Sequence: ELSANHVLAERRRR | ||||||
Domain | 483-532 | bHLH | ||||
Sequence: ELSANHVLAERRRREKLNERFIILRSLVPFVTKMDKASILGDTIEYVKQL | ||||||
Region | 497-532 | Helix-loop-helix motif | ||||
Sequence: EKLNERFIILRSLVPFVTKMDKASILGDTIEYVKQL | ||||||
Region | 547-570 | Disordered | ||||
Sequence: EIDQRSRSSGDPQRSGAKAATDKR |
Sequence similarities
Belongs to the bHLH protein family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length689
- Mass (Da)76,277
- Last updated2018-06-20 v1
- Checksum3A8F10513F191041
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 87 | in Ref. 1; QAT77714 | ||||
Sequence: Q → P | ||||||
Compositional bias | 247-271 | Acidic residues | ||||
Sequence: EQEQEQEEDEDDDDDDDDEEEAESD | ||||||
Sequence conflict | 256 | in Ref. 1; QAT77714 | ||||
Sequence: E → D | ||||||
Sequence conflict | 355 | in Ref. 1; QAT77714 | ||||
Sequence: P → A | ||||||
Sequence conflict | 376 | in Ref. 1; QAT77714 | ||||
Sequence: E → D | ||||||
Compositional bias | 461-480 | Polar residues | ||||
Sequence: NSPKSATAADSASRFRKPTP |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MH643776 EMBL· GenBank· DDBJ | QAT77714.1 EMBL· GenBank· DDBJ | mRNA | ||
NKQK01000017 EMBL· GenBank· DDBJ | PSS06386.1 EMBL· GenBank· DDBJ | Genomic DNA |