A0A2R6Q0L3 · A0A2R6Q0L3_ACTCC

Function

function

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site461D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site871D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site122ATP (UniProtKB | ChEBI)
Binding site172ATP (UniProtKB | ChEBI)
Binding site1831D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site204-215ATP (UniProtKB | ChEBI)
Binding site2151D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site230ATP (UniProtKB | ChEBI)
Binding site295Mg2+ 1 (UniProtKB | ChEBI)
Binding site310Mg2+ 2 (UniProtKB | ChEBI)
Binding site310Mg2+ 1 (UniProtKB | ChEBI)
Binding site3121D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)
Binding site312Mg2+ 2 (UniProtKB | ChEBI)
Binding site3161D-myo-inositol 1,3,4-trisphosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functioninositol-1,3,4-trisphosphate 5-kinase activity
Molecular Functioninositol-1,3,4-trisphosphate 6-kinase activity
Molecular Functioninositol-3,4,5,6-tetrakisphosphate 1-kinase activity
Molecular Functionmagnesium ion binding
Biological Processinositol trisphosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inositol-tetrakisphosphate 1-kinase
  • EC number

Gene names

    • ORF names
      CEY00_Acc23855

Organism names

Accessions

  • Primary accession
    A0A2R6Q0L3

Proteomes

Genome annotation databases

Subcellular Location

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain37-116Inositol-tetrakisphosphate 1-kinase N-terminal
Domain136-332Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp

Sequence similarities

Belongs to the ITPK1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    351
  • Mass (Da)
    39,739
  • Last updated
    2018-06-20 v1
  • Checksum
    697699C130189FA4
MRLKEETEYEEEKREESMVVQKYSIGGGLPQPTKAVVVGYALTSKKKKSFLQPKLEFLARNKGILFVAIDPNRPLSEQGPFDIVLHKLSGKEWRQILEDYRKTHPEVTVLDPPDAIQHVYNRQFMLQDVADLNLSDAYGTVGVPRQLVIKKDPSSIPDDVNRAGLKLPLVAKPLVVDGSAKSHELSLAYDQYSLQILEPPLVVQEFVNHGGVLFKVYIVGEAIKVVRRFSLPDVSKRELSTNAGVFRFPRVSCAAASADDADLDPGVAELPPRPLLERLARELRRRLGLRLFNLDMIREHGTRDRYYVIDINYFPGYGKMPGYEHIFTDFLLGLVQSKHKKRVAKPVEEPV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NKQK01000021
EMBL· GenBank· DDBJ
PSR99955.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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