A0A2R6PB27 · A0A2R6PB27_ACTCC

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyruvate (UniProtKB | Rhea| CHEBI:15361 )

Note: Binds 1 pyruvoyl group covalently per subunit.

Pathway

Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site10substrate
Binding site70substrate
Site70-71Cleavage (non-hydrolytic); by autolysis
Active site71Schiff-base intermediate with substrate; via pyruvic acid
Active site85Proton donor; for catalytic activity
Binding site228substrate
Active site234Proton acceptor; for processing activity
Active site247Proton acceptor; for processing activity
Binding site251substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylmethionine decarboxylase activity
Biological Processspermidine biosynthetic process
Biological Processspermine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    S-adenosylmethionine decarboxylase proenzyme
  • EC number

Gene names

    • ORF names
      CEY00_Acc31250

Organism names

Accessions

  • Primary accession
    A0A2R6PB27

Proteomes

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_50423231771-70S-adenosylmethionine decarboxylase beta chain
Modified residue71Pyruvic acid (Ser); by autocatalysis
ChainPRO_504232317871-358S-adenosylmethionine decarboxylase alpha chain

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the eukaryotic AdoMetDC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    358
  • Mass (Da)
    39,072
  • Last updated
    2018-06-20 v1
  • Checksum
    8017297971C30F63
MALAVSAIGFEGYEKRLEISFFEPTIFADPKGRGLRSLSKAQLDEFLGPAECTIVSSLSNDHVDSYVLSESSLFVYSYKIIIKTCGTTKLLLAIPPILKLADTLFLTVRSVRYTRGSFIFPAAQSYPHRNFSEEVEVLDSYFGKLGSGGNAFVMGSFNKLQKWHVYSASAESVCSGNPVYTLEMCMTGLDKEMASVFYINQSGSAAVMTCTSGIRKILPESKICDFDFEPCGYSMNAIEGAAISTIHITPEDGFSYASFEAVGYDPKLVDLDLLVERVLACFNPSEFSISVHADVSSKLLEHTCSLGVKGFCLGDSSYEELGTTGGSMVYQKFVKTVGCGSPRSILNSCWKDEDGEME

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NKQK01000027
EMBL· GenBank· DDBJ
PSR88222.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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