A0A2R6P9N0 · A0A2R6P9N0_ACTCC
- ProteinSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids280 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Catalytic activity
- a quinone + succinate = fumarate + a quinol
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 [2Fe-2S] cluster.
Note: Binds 1 [3Fe-4S] cluster.
Note: Binds 1 [4Fe-4S] cluster.
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex II (succinate dehydrogenase) | |
Molecular Function | 2 iron, 2 sulfur cluster binding | |
Molecular Function | 3 iron, 4 sulfur cluster binding | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | electron transfer activity | |
Molecular Function | metal ion binding | |
Molecular Function | succinate dehydrogenase (quinone) activity | |
Biological Process | ferredoxin metabolic process | |
Biological Process | respiratory electron transport chain | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > Ericales > Actinidiaceae > Actinidia
Accessions
- Primary accessionA0A2R6P9N0
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
Component of complex II composed of eight subunits in plants: four classical SDH subunits SDH1, SDH2, SDH3 and SDH4 (a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.), as well as four subunits unknown in mitochondria from bacteria and heterotrophic eukaryotes.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 49-135 | 2Fe-2S ferredoxin-type | ||||
Sequence: FQIYRWSPDDPKKPELRDYQIDLKECGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNIDGCNGLACLTKIPSGSSMATITPL | ||||||
Domain | 181-211 | 4Fe-4S ferredoxin-type | ||||
Sequence: DRAKLDGMYECILCACCSTSCPSYWWNPESY |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length280
- Mass (Da)31,553
- Last updated2018-06-20 v1
- Checksum23CED39E71FF9CE6
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NKQK01000027 EMBL· GenBank· DDBJ | PSR87527.1 EMBL· GenBank· DDBJ | Genomic DNA |