A0A2R6P6N8 · A0A2R6P6N8_ACTCC
- ProteindCTP pyrophosphatase 1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids132 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
Catalytic activity
- dCTP + H2O = dCMP + diphosphate + H+
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | dCTP diphosphatase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | dCTP catabolic process | |
Biological Process | DNA protection |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedCTP pyrophosphatase 1
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > Ericales > Actinidiaceae > Actinidia
Accessions
- Primary accessionA0A2R6P6N8
Proteomes
Genome annotation databases
Subcellular Location
Interaction
Structure
Sequence
- Sequence statusComplete
- Length132
- Mass (Da)14,743
- Last updated2018-06-20 v1
- MD5 Checksum91AC3EDDB5A8325ECF3A5343D5D1E5A6
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NKQK01000028 EMBL· GenBank· DDBJ | PSR86311.1 EMBL· GenBank· DDBJ | Genomic DNA |