A0A2R6AU93 · A0A2R6AU93_9ARCH

Function

function

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site43D-ribose 5-phosphate (UniProtKB | ChEBI)
Active site100Schiff-base intermediate with D-ribose 5-phosphate
Binding site172D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site184D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site237D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site258-259D-ribose 5-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Processamino acid metabolic process
Biological Processpyridoxal phosphate biosynthetic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxS
  • EC number
  • Short names
    PLP synthase subunit PdxS
  • Alternative names
    • Pdx1

Gene names

    • Name
      pdxS
    • ORF names
      B9Q03_07845

Organism names

Accessions

  • Primary accession
    A0A2R6AU93

Proteomes

Interaction

Subunit

In the presence of PdxT, forms a dodecamer of heterodimers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain26-235PdxS/SNZ N-terminal

Sequence similarities

Belongs to the PdxS/SNZ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    318
  • Mass (Da)
    35,074
  • Last updated
    2018-06-20 v1
  • Checksum
    1A960A0B5AB47C23
MVSIIGYPFSERVPEWRNGVGVQGTVLVKRGFAHMLKHGVVMDVTNVEQAQIAEDAGAVAVMVLDKLPYDVRKAGGVARTASLRIIEDVMDHITIPVMAKCRIGHTYEAEVLQAIGVDMIDESEVLTPADDQRHIWKWSFKTPFVNGARSLGEALRRIEEGAAMIRTKGEPGTGNVAEAVKHFRLIKKELADVRALYLEGDYQELMLRAREMQVSLELVVETARLNRLPVVNFAAGGIATPADAAEMMKLGADGIFVGSGIFKSRDPFERARAIVEATSFYDEPEVVAEVQKSVDETKSMEGLDENTMVFKMQERGPN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NEXE01000080
EMBL· GenBank· DDBJ
PSN89932.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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