A0A2R4G5N1 · A0A2R4G5N1_BIFAD
- ProteinUvrABC system protein A
- GeneuvrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids982 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 68-75 | ATP (UniProtKB | ChEBI) | |||
Binding site | 683-690 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | excinuclease repair complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Molecular Function | excinuclease ABC activity | |
Molecular Function | zinc ion binding | |
Biological Process | nucleotide-excision repair | |
Biological Process | SOS response |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameUvrABC system protein A
- Short namesUvrA protein
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Bifidobacteriales > Bifidobacteriaceae > Bifidobacterium
Accessions
- Primary accessionA0A2R4G5N1
Proteomes
Subcellular Location
Interaction
Subunit
Forms a heterotetramer with UvrB during the search for lesions.
Structure
Family & Domains
Features
Showing features for domain, zinc finger.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 651-979 | ABC transporter | |||
Zinc finger | 782-808 | C4-type | |||
Sequence similarities
Belongs to the ABC transporter superfamily. UvrA family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length982
- Mass (Da)109,357
- Last updated2018-06-20 v1
- MD5 ChecksumD41DA7E97F269BED3399BA3202F5009C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP028341 EMBL· GenBank· DDBJ | AVT46133.1 EMBL· GenBank· DDBJ | Genomic DNA |