A0A2R3JL50 · A0A2R3JL50_9LACO
- ProteinSignal recognition particle receptor FtsY
- GeneftsY
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids445 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 246-253 | GTP (UniProtKB | ChEBI) | |||
Binding site | 328-332 | GTP (UniProtKB | ChEBI) | |||
Binding site | 392-395 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | signal recognition particle binding | |
Biological Process | SRP-dependent cotranslational protein targeting to membrane |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSignal recognition particle receptor FtsY
- EC number
- Short namesSRP receptor
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus
Accessions
- Primary accessionA0A2R3JL50
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 13-68 | Disordered | |||
Compositional bias | 17-68 | Polar residues | |||
Region | 115-142 | Disordered | |||
Domain | 140-221 | Signal recognition particle SRP54 helical bundle | |||
Domain | 238-430 | AAA+ ATPase | |||
Domain | 239-440 | SRP54-type proteins GTP-binding | |||
Sequence similarities
Belongs to the GTP-binding SRP family. FtsY subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length445
- Mass (Da)46,871
- Last updated2018-06-20 v1
- Checksum384FA47709BF7627
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 17-68 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP027190 EMBL· GenBank· DDBJ | AVK60309.1 EMBL· GenBank· DDBJ | Genomic DNA |