A0A2P7YUD9 · A0A2P7YUD9_9ASCO

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.26 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

Features

Showing features for active site.

1783100200300400500600700
TypeIDPosition(s)Description
Active site751Glycyl thioester intermediate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcellular bud tip
Cellular Componentcytosolic ribosome
Cellular Componentendosome membrane
Cellular ComponentGolgi apparatus
Cellular Componentnucleus
Cellular ComponentRSP5-BUL ubiquitin ligase complex
Cellular Componentubiquitin ligase complex
Molecular Functionphosphatidylinositol binding
Molecular Functionubiquitin binding
Molecular Functionubiquitin-ubiquitin ligase activity
Biological Processcellular response to heat
Biological Processcellular response to L-arginine
Biological Processchromatin organization
Biological Processfree ubiquitin chain polymerization
Biological Processmitochondria-associated ubiquitin-dependent protein catabolic process
Biological Processmitochondrion organization
Biological Processnonfunctional rRNA decay
Biological Processpoly(A)+ mRNA export from nucleus
Biological Processpositive regulation of fatty acid biosynthetic process
Biological Processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Processpositive regulation of receptor-mediated endocytosis
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processprotein K63-linked ubiquitination
Biological Processprotein quality control for misfolded or incompletely synthesized proteins
Biological Processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Biological Processregulation of actin cytoskeleton organization
Biological Processregulation of dolichol biosynthetic process
Biological Processregulation of ergosterol biosynthetic process
Biological Processregulation of mRNA export from nucleus
Biological Processregulation of multivesicular body size
Biological Processregulation of nitrogen utilization
Biological Processregulation of phosphate metabolic process
Biological Processregulation of protein localization
Biological Processregulation of ribosomal large subunit export from nucleus
Biological Processregulation of rRNA processing
Biological Processregulation of tRNA export from nucleus
Biological Processregulation of tRNA processing
Biological Processregulation of ubiquinone biosynthetic process
Biological Processribophagy
Biological Processubiquitin-dependent endocytosis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    E3 ubiquitin-protein ligase
  • EC number

Gene names

    • ORF names
      C7M61_001383

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • B12108
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Metschnikowiaceae > Metschnikowiaceae incertae sedis > Candida/Metschnikowiaceae

Accessions

  • Primary accession
    A0A2P7YUD9

Proteomes

Organism-specific databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain1-105C2
Region130-183Disordered
Domain195-228WW
Region221-285Disordered
Compositional bias228-254Basic and acidic residues
Compositional bias260-285Polar residues
Domain306-339WW
Domain361-394WW
Domain450-783HECT

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    783
  • Mass (Da)
    89,074
  • Last updated
    2018-05-23 v1
  • Checksum
    4C6756F9DE3F3C7B
MTKVNVKVVAAESLYKRDVFRQPDPFAVITVDGDQTITTKTAKRTLNPYWNESFLLSASEDSILAIQVFDQRKFKKKDQGFLGVVNVRVGDVIDLSLSGSEETITRDLKKSNENLAVSGRVIIVLSHNTNPSSAPAANGSAAPAPRASSSARNSVPNSTPAASSAPPAAANGNGNSNGNGEQFTKQYSSFEDQYGRLPPGWERRTDNFGRTYYVDHNSRTTTWERPTLDQSETERGQQRENHTEAERRQHRGRTLPGEAPQSPTLPSASTSTSNNVTVNSTGANTPVSPAAAVSMAATGGTTRGLGELPTGWEQRFTNEGRPYFVDHNTRTTTWVDPRRQQYIRTFGPNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIKVRRDHIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHDMFNPFYCLFEYSSHDNYTLQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVNLQDMEGVDAEFYRSLQWILDNDITDILDLTFSAEDDKFGEIVEVDLKPGGRDIEVTEENKAEYVELISEWKIHKRIELQFQAFIDGFNELIPQELVNVFDERELELLIGGLAEIDVEDWKKHTDYRGYQETDQVIQWFWQCIKEWDSVQKARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEPNQLPKSHTCFNRVDFPPYTSYESMKQKLTLAVEETVGFGQE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias228-254Basic and acidic residues
Compositional bias260-285Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PYFQ01000002
EMBL· GenBank· DDBJ
PSK39584.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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