A0A2P6W228 · A0A2P6W228_9EURY
- ProteinAspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
- GenegatC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
Catalytic activity
- ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H+ + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate
- ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H+ + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity | |
Molecular Function | ATP binding | |
Molecular Function | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity | |
Molecular Function | transferase activity | |
Biological Process | glutaminyl-tRNAGln biosynthesis via transamidation | |
Biological Process | regulation of translational fidelity | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
- EC number
- Short namesAsp/Glu-ADT subunit C
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Candidatus Nanohaloarchaea
Accessions
- Primary accessionA0A2P6W228
Proteomes
Interaction
Subunit
Heterotrimer of A, B and C subunits.
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 47-81 | Basic and acidic residues | ||||
Sequence: DVEPAFHPVETDPKTREDEVEETLDKDEVLQNTEN | ||||||
Region | 47-92 | Disordered | ||||
Sequence: DVEPAFHPVETDPKTREDEVEETLDKDEVLQNTENEEDGYFKGPSA |
Sequence similarities
Belongs to the GatC family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length92
- Mass (Da)10,588
- Last updated2018-05-23 v1
- Checksum56F7331BF13D2A6D
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 47-81 | Basic and acidic residues | ||||
Sequence: DVEPAFHPVETDPKTREDEVEETLDKDEVLQNTEN |