A0A2P6W086 · A0A2P6W086_9EURY
- ProteinDNA polymerase II small subunit
- GenepolB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids540 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
Catalytic activity
- a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | DNA polymerase complex | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | single-stranded DNA 3'-5' DNA exonuclease activity | |
Biological Process | DNA catabolic process | |
Biological Process | DNA strand elongation involved in DNA replication |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase II small subunit
- EC number
- Short namesPol II
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Candidatus Nanohaloarchaea
Accessions
- Primary accessionA0A2P6W086
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Heterodimer of a large subunit and a small subunit.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 46-135 | Disordered | ||||
Sequence: MLEDLREKREESNSSALNSGSPKSNGSSPNGHSGQKTVRKKKDASTGEMGNSRKQEENTSENSEPKRISTDDVNSSKANQNIEILDERDR | ||||||
Compositional bias | 59-79 | Polar residues | ||||
Sequence: SSALNSGSPKSNGSSPNGHSG | ||||||
Compositional bias | 81-116 | Basic and acidic residues | ||||
Sequence: KTVRKKKDASTGEMGNSRKQEENTSENSEPKRISTD | ||||||
Domain | 283-485 | DNA polymerase alpha/delta/epsilon subunit B | ||||
Sequence: YISDLHLGSKDTRHDKFMEFADWLKSENAEKVGYVVIGGDIVEGVGSYPGQKEELEVTDIYKQYQLFEDWVEKVPEHIQLIVGPGNHDITRLAEPQPRLPEKAMPEIYDYNNVHFVQNPQTVRLHAIRSKGIKNLIYHGYSFDDHVDRIQALREKAYQEPYHVMIDLLKRRHLAPSYGSNQLSPEGEDHLAITEEPDVFVSGH |
Sequence similarities
Belongs to the DNA polymerase delta/II small subunit family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length540
- Mass (Da)61,575
- Last updated2018-05-23 v1
- Checksum4C552329355AF803
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 59-79 | Polar residues | ||||
Sequence: SSALNSGSPKSNGSSPNGHSG | ||||||
Compositional bias | 81-116 | Basic and acidic residues | ||||
Sequence: KTVRKKKDASTGEMGNSRKQEENTSENSEPKRISTD |