A0A2P6MK81 · A0A2P6MK81_ALKUR
- ProteinHTH-type transcriptional regulator MntR
- GenemntR
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids141 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Central regulator of manganese homeostasis.
Activity regulation
DNA binding is strongly activated by Mn2+.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 8 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 11 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 77 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 99 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 99 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 102 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 102 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 103 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | DNA binding | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | manganese ion binding | |
Molecular Function | protein dimerization activity | |
Biological Process | intracellular manganese ion homeostasis |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameHTH-type transcriptional regulator MntR
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Alkalicoccus
Accessions
- Primary accessionA0A2P6MK81
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-63 | HTH dtxR-type | ||||
Sequence: MPTPSMEDYLERIYQLIDEKGYARVSDIAGALEVHPSSVTKMVQKLDASEYLVYEKYRGLVLT |
Sequence similarities
Belongs to the DtxR/MntR family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length141
- Mass (Da)16,475
- Last updated2018-05-23 v1
- Checksum949F2CAA1934FAC3
Keywords
- Technical term