A0A2P2I5Q9 · A0A2P2I5Q9_9CRUS

  • Protein
    AF4/FMR2 family member lilli
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

function

Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentsuper elongation complex
Molecular FunctionDNA binding
Biological Processperiodic partitioning by pair rule gene
Biological Processregulation of gene expression

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    AF4/FMR2 family member lilli
  • Alternative names
    • Protein lilliputian

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Multicrustacea > Malacostraca > Eumalacostraca > Peracarida > Amphipoda > Amphilochidea > Lysianassida > Lysianassidira > Lysianassoidea > Lysianassidae > Hirondellea

Accessions

  • Primary accession
    A0A2P2I5Q9

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-52Acidic residues
Region1-369Disordered
Compositional bias55-69Polar residues
Compositional bias116-144Polar residues
Compositional bias271-290Basic and acidic residues
Compositional bias316-346Polar residues
Compositional bias354-369Polar residues
Compositional bias401-419Polar residues
Region401-420Disordered
Compositional bias435-463Basic and acidic residues
Region435-594Disordered
Compositional bias479-516Basic and acidic residues
Compositional bias535-566Basic and acidic residues
Compositional bias567-594Polar residues
Domain725-902AF4/FMR2 C-terminal homology
Region858-883Disordered
Compositional bias859-883Polar residues
Domain903-1021AF4/FMR2 C-terminal homology
Region930-950Disordered

Sequence similarities

Belongs to the AF4 family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    1,051
  • Mass (Da)
    114,754
  • Last updated
    2018-05-23 v1
  • MD5 Checksum
    C90A641A7AB7F504FEF94305E1456605
DDDDHDGDDDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDSNNSKSESESSVSSSGEESSSSSEDELEEGEVVENENEGQKSSSPAKTIGDTQPKLPDLPEAQPVPAEVQSETSCSWNLSRLWKNGTTDNSSTSTTKRHSSEKRSMRTPHQKSPRVPVAVHSPILSEESSDEAPPPRRTPQIAAVTRPVERSRHKPSSDSDSGPPPTHIDVTKKHTKRAPVKAPPRVQKPVAKPKQTGRGRPRKTGVPTKAELAAESKAKSRQFLSTDDSSDSDNEIKPKTPVKPTKAATTTRRSTTSRNAKDTPHENKSPINVCTPVSTMAVPAVPSSNHKVTPSRVTRENTSKDVKITSSGSIQCSQNEHVEKSPAKLSSFGGQFLFSELSLLSATNIPDAKPEMTKSSNSRTSDGNKKRCLFNLFGDKKDKMNKIKDTDQDQKIKEQTAVKKSETVENNKEKPSVAVDVPIAQRRGRDNGQSKKGKLDSEGIDPTKLNVSVKRKRDDTKESVSVSESDSTHLSSKKSKKSHRDTDRHSIDTQKSKVHRSSDNNSDNDSKRNKGNNAKISTKSRSATPASASNTPLHDATVNSNFSHDLRVPLEGETSVAYESRQSDDVSQHKRAMASPVSSCNGAATTTTTTTVAAAVEHPAAIIRSNVASARDNPIRCSNTPSMYDLTPPPLIGKPVKLPTPISSCFPCIGELEGMSIEEIFFKFFGNSSDMRQNDNTPYLDRAKHLKRKADDVELDRTCQGTKYLEAVLYFILSGKSMENDASLIQSAVTMYTDTMNLITWVPSVFKRTMIQPQYNQQDECSAKLSVLCVLCQCILSLKVFNMRRHEVKDSRIVLAEHSSKIAKEKLPSSGSTPSNNANSTPSNTATTSCSSSSAAAAAAAADHTLNSNRVAVSPSASSATPSPAGSIGSDCSSGYLTSTASQPPPTPATPNSNKPEIAPEIYAHLFKLYTVNNFLINSHEMWLEAQRIVTDYKLELFFGCLDKVISPFTLHTDTRHLVCYIMAALRDIDDTLMRLKEEGKYAKKDEQRHHAEAGAQ

Features

Showing features for non-terminal residue, compositional bias.

Type
IDPosition(s)Description
Non-terminal residue1
Compositional bias1-52Acidic residues
Compositional bias55-69Polar residues
Compositional bias116-144Polar residues
Compositional bias271-290Basic and acidic residues
Compositional bias316-346Polar residues
Compositional bias354-369Polar residues
Compositional bias401-419Polar residues
Compositional bias435-463Basic and acidic residues
Compositional bias479-516Basic and acidic residues
Compositional bias535-566Basic and acidic residues
Compositional bias567-594Polar residues
Compositional bias859-883Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
IACF01003748
EMBL· GenBank· DDBJ
LAB69358.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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