A0A2P1H677 · A0A2P1H677_9BIVA
- ProteinSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids288 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Catalytic activity
- a quinone + succinate = fumarate + a quinol
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 [2Fe-2S] cluster.
Note: Binds 1 [3Fe-4S] cluster.
Note: Binds 1 [4Fe-4S] cluster.
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | 2 iron, 2 sulfur cluster binding | |
Molecular Function | 3 iron, 4 sulfur cluster binding | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | electron transfer activity | |
Molecular Function | metal ion binding | |
Molecular Function | succinate dehydrogenase (quinone) activity | |
Biological Process | respiratory electron transport chain | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
- EC number
Encoded on
- Mitochondrion
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Bivalvia > Autobranchia > Heteroconchia > Palaeoheterodonta > Unionida > Unionoidea > Hyriidae > Diplodon
Accessions
- Primary accessionA0A2P1H677
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 37-130 | 2Fe-2S ferredoxin-type | |||
Domain | 175-205 | 4Fe-4S ferredoxin-type | |||
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length288
- Mass (Da)32,042
- Last updated2018-05-23 v1
- MD5 Checksum747B4C9B8711D0715FD8131D9CC7B16E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MF771092 EMBL· GenBank· DDBJ | AVN67027.1 EMBL· GenBank· DDBJ | mRNA |