A0A2P1GMC4 · A0A2P1GMC4_9VIRU

Function

function

Responsible for the cleavage of the polyprotein into functional products.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenthost cell membrane
Cellular Componentmembrane
Molecular Functionnucleotide binding
Molecular FunctionRNA binding
Molecular FunctionRNA-dependent RNA polymerase activity
Molecular Functionserine-type peptidase activity
Biological ProcessDNA-templated transcription
Biological Processproteolysis
Biological Processviral RNA genome replication
Biological Processviral translational frameshifting

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Non-structural polyprotein 1AB

Organism names

  • Taxonomic identifier
  • Strain
    • DTHH2075
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Pisuviricota > Stelpaviricetes > Stellavirales > Astroviridae

Accessions

  • Primary accession
    A0A2P1GMC4

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane174-196Helical
Transmembrane246-265Helical
Transmembrane277-298Helical
Transmembrane304-322Helical
Transmembrane329-346Helical

Keywords

  • Cellular component

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region834-869Disordered
Compositional bias835-850Polar residues
Domain1064-1188RdRp catalytic
Compositional bias1317-1334Basic and acidic residues
Region1317-1360Disordered
Compositional bias1345-1360Basic and acidic residues

Sequence similarities

Belongs to the astroviridae polyprotein 1AB family.
Belongs to the peptidase S1B family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,360
  • Mass (Da)
    152,506
  • Last updated
    2018-05-23 v1
  • Checksum
    02B8762B1C4078AE
MANVTNTTTTTQAGAGQTGFTAFETPTQVLMNAPAAAAAAVSKTDTRQGDLEKLLKEYKELTGNDYTAGIVRPKTQFPVSNGAVHHAQVDISDSEDEEEELFVGGKTKYDPNAPLVLSTPPSAMNFRKALAKSEETVLRYTQKLLKEGKVAEEPKKEEEEVTVKEPKDRPFIKWLFIFIISLGIVGFLTVLSLQVIHYLRDDHVHVPHTKLQPEGKQFKVTYSYTTTGRPITVSTTVPKGPKLDRLMVVMYALMLLMHFLTKYFTPAGFIMCALIPINSVGIYALSMFAPTFIAGFLLTMGPTSFIPLSVLTTVTSILWRIFKGDTNWALADCVLYAAGVGGYQLWALLELPFFPVSKLLECAIVFGIVLGTKIALLSLPSVKKIYHWSGETVTSTYVDLKHNLGQAASTFNLGIGPLFKSAKTPQQNHGGVVHDGVRLRRTRQSGNAEQPYQRFVPQKESKSEIWPNGVGQPILNTTSDVRTFLTNLSSPPCYDKEVATGGPQFPVKILDYFIQVLDDRGEFVGHAVPFMGAVVILKHVVPNKKVGDKILVIFRGNEYHLKILKQTLPRQPGQSEVLYWCNPPPGCESVRREKNPMPQPIILRSYVNMEHCISPGSTITGFKHTANTSGGTSGSPIYSTNGNLVGIHWGGIGSVNGYVGVQAIIDSLSGGIDQEAKPKYIKRVGRGKGKGKKKKGLGKFFTNEEYDDLINNKGMTKQQIWDLIDYMKHTSNDYDEDEYEAVIQLESGHQIPINSPLEEWFVVTYYHHIMNNPDFCVCNEPGCKCSDFQERLEDEPTEVIGNGPDWQMIAPKNPRSPLAITRGGKTRELFGLTSGDFRPTSQSGTYGSLGQVKVNRRPDHTPRGDPISNYWGDVGQTQTHFPPTWTARHHQSGFDKFTPTDGNCGAADASIIRAAETLSRKISRAIFETEGKYGVQKTPIEAVTKPTESNPGWPYLNDYNSESAFALENLDSYAEMYDAMLDDSWLPVWYSFLKNEVVTKQKLDEGNFRVITCPPCVFSRIQGTYDQDLNRWFKEHPGLLHSMVGFTPFDGQLTNYMRKLGGYKYYVEKDFKRFDGSLPEHLMRMVRKIRANQFAPEALDSDDLKRLKFIETALTNRPTLTTAGTLHFCAKGNASGQVSTSSDNCIANILLHYMMYQEVYGLEPDDVDFYVYGDDFIGGMNVKPDPVAEEQWFLLRFGMILPSEKFKWSRSLDGLSFCGFVIHGDDVDGYYPVYKPEKILSNLMNPAIAVKDPYVMYAKMLCVTLLLWKGPWGDKLYERLIELARIINAWVPSASFFDKLVGGGPKKDTKIQWQEKRIITQPKRDQQPELSPKPQRKRRPRRRDNPQKDRNLTKLNPLKE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias835-850Polar residues
Compositional bias1317-1334Basic and acidic residues
Compositional bias1345-1360Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MG599887
EMBL· GenBank· DDBJ
AVM87143.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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