A0A2P1DP89 · MACR_PENTR

  • Protein
    Transcription factor macR
  • Gene
    macR
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of macrophorins, isoprenoid epoxycyclohexenones containing cyclized drimane moieties.

Miscellaneous

The macrophorins cluster contains a single gene insertion (encoding for the terpene cyclase macJ) compared with the yanuthone cluster that produces the linear compound yanuthone.

Features

Showing features for dna binding.

1853100200300400500600700800
TypeIDPosition(s)Description
DNA binding18-45Zn2-C6 fungal-type

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription factor macR
  • Alternative names
    • Macrophorins biosynthesis cluster protein R

Gene names

    • Name
      macR

Organism names

  • Taxonomic identifier
  • Strain
    • LM2
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Penicillium

Accessions

  • Primary accession
    A0A2P1DP89

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004540931-853Transcription factor macR

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias54-74Basic and acidic residues
Region54-122Disordered
Compositional bias102-116Polar residues
Compositional bias138-165Polar residues
Region138-166Disordered
Compositional bias734-761Polar residues
Region734-775Disordered
Region833-853Disordered

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    853
  • Mass (Da)
    94,426
  • Last updated
    2018-05-23 v1
  • Checksum
    CD64932694D4F64D
MPLSEPRQIKKPRLSLSCIVCRRRKVRCGREQPECANCVRMKENCVYRTMVRDESTGRVRPVSPQDKDSRVSTSDARPDLPWPHWGRDTNAPYPDKPSRPPSRPQVSANASPSPQRQEPYPTVPSWEEAIQLPSYRDANAPQINGSSTTTRDPSPAPSTSLFPTPSDHPCRDYLSIRRGGRVRYVGQTFWGFVAGKESLSDDFFDENRHAHPDLPLPHISSMGMFNLLRSLPTKPVSDTLLETFFLAVWPLVPLLHPPSLQADYDEFWEWCRNSENALPSDKLRDDPTLICLLFAVLYCGASAAPAATWANTNLQGLQKETTVSHLKSAYTTSLSLCQHQEHPTLNTLVSNLLTGPFLDRPFEPMRSLVNVSTTVRIAQTMGLHREGAWSALSSVDREIRRRVWWHIVWLDVQSSISTGLTPCCGNEALDAVGMVGTDHVEPSNIPAGLSPPNELVTNRQSVAMLYAIGRFQTARLQARIVAHLQSAHDPSQDGFGELITDSKELLQKIDSLIARVPTQGIPEMGYIPSRLANASPSTQPLLYKDDPSQPTVFSAWTRIMLTLLKSEMAILLQKPFLPPPDSANPQSLKSWTSMAQLCVNYLRIYLQLYQAPAFSPYAWFCCSHYGPLQCVFITLMYLHYFQHSGETTLARYCVDEVIHHCVAQYQAPDPSSTRTSPDDTDSNGGKLRMPLAIQVLVDLHERLDSSLGPEDRAPPLDLIECQARFSMSHLATKASDLRATSDQPSSDVSSTTRTHHNCETPPITTGAPPVAAGNKPVPPNSVFVAGSDSGLDMDFLATISDLEAWSSSLILESDNLLARPDDMTPDHAVITRLGSQSTASGRRGLPDGLDFPG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias54-74Basic and acidic residues
Compositional bias102-116Polar residues
Compositional bias138-165Polar residues
Compositional bias734-761Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MF989995
EMBL· GenBank· DDBJ
AVK70096.1
EMBL· GenBank· DDBJ
Genomic DNA
MH388470
EMBL· GenBank· DDBJ
QBC75452.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp