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A0A2N6N7A4 · A0A2N6N7A4_9COXI

  • Protein
    Phosphopantetheine adenylyltransferase
  • Gene
    coaD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site10substrate
Binding site10-11ATP (UniProtKB | ChEBI)
Binding site18ATP (UniProtKB | ChEBI)
Site18Transition state stabilizer
Binding site42substrate
Binding site74substrate
Binding site88substrate
Binding site89-91ATP (UniProtKB | ChEBI)
Binding site99ATP (UniProtKB | ChEBI)
Binding site124-130ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • ORF names
      CLERM_083

Organism names

Accessions

  • Primary accession
    A0A2N6N7A4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-134Cytidyltransferase-like

Sequence similarities

Belongs to the bacterial CoaD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    160
  • Mass (Da)
    18,053
  • Last updated
    2018-04-25 v1
  • MD5 Checksum
    D6D46D81E50EB9E22392C238CD18F28A
MKAVAVYPGTFDPLTKGHVDIVERAILLFEKIIVACASTSRKKPYLSLAERIGLIKEVFADLINIEVVPLEGLLVDFAKQHNAKIILRGLRTVSDFDYEFRLAHINHYLSPEIQTIFLPAKENYSHISGTLVREIVELGGDISLFVPPLFAQRLVKRKKI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NSHJ01000081
EMBL· GenBank· DDBJ
PMB54867.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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