A0A2N2R030 · A0A2N2R030_9PROT

Function

function

Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.

Miscellaneous

The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site55-57substrate
Binding site64Zn2+ (UniProtKB | ChEBI)
Binding site68Zn2+ (UniProtKB | ChEBI)
Binding site68substrate
Binding site97-98substrate
Binding site123-125substrate
Binding site128substrate
Binding site178Zn2+ (UniProtKB | ChEBI)
Binding site178substrate
Binding site186Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarbohydrate derivative binding
Molecular FunctionD-sedoheptulose 7-phosphate isomerase activity
Molecular Functionzinc ion binding
Biological Processcarbohydrate metabolic process
Biological ProcessD-glycero-D-manno-heptose 7-phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoheptose isomerase
  • EC number
  • Alternative names
    • Sedoheptulose 7-phosphate isomerase

Gene names

    • Name
      gmhA
    • ORF names
      CVU33_19055

Organism names

Accessions

  • Primary accession
    A0A2N2R030

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain40-200SIS

Sequence similarities

Belongs to the SIS family. GmhA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    200
  • Mass (Da)
    20,942
  • Last updated
    2018-04-25 v1
  • MD5 Checksum
    45D4815C00C3F255158DA1CD2F425272
MAADASPVALERQHFEDSAQTKLNAVEMMAAPIAAAIETMTNCLINGGKILACGNGGSAGDAQHFAAELIGRFEAERQELAAIALTTDTSIITAVANDYSFSQIFSRQVRGLGHAGDVLLAISTSGNSANVIEAIKSAHEHDMHIVALTGKGGGLIGDMLRDDDIHLCVPAERTARIQETHLLAIHCLCDGIDALLLGVE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PHCF01000152
EMBL· GenBank· DDBJ
PKO36303.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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