A0A2N0UTD6 · A0A2N0UTD6_9FIRM
- ProteinNAD kinase
- GeneppnK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids285 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Catalytic activity
- ATP + NAD+ = ADP + H+ + NADP+
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 69 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 69-70 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: DG | ||||||
Binding site | 74 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 141-142 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: ND | ||||||
Binding site | 152 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 169 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 171 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 182-187 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: TAYSLS |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Molecular Function | NAD+ kinase activity | |
Biological Process | NAD metabolic process | |
Biological Process | NADP biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Oscillospiraceae > Ruminococcus
Accessions
- Primary accessionA0A2N0UTD6
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length285
- Mass (Da)31,754
- Last updated2018-04-25 v1
- ChecksumB1156BD2D40B3ADA
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WNAH01000001 EMBL· GenBank· DDBJ | MTR78239.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NNBY01000031 EMBL· GenBank· DDBJ | PKD30272.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
QSEV01000005 EMBL· GenBank· DDBJ | RGZ96551.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
QSIY01000001 EMBL· GenBank· DDBJ | RHD25156.1 EMBL· GenBank· DDBJ | Genomic DNA |