A0A2M7MHR4 · A0A2M7MHR4_9BACT

Function

function

Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site495-501ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionracemase and epimerase activity, acting on amino acids and derivatives
Molecular Functiontetrahydrofolylpolyglutamate synthase activity
Molecular FunctionUDP-N-acetylmuramoylalanine-D-glutamate ligase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    UDP-N-acetylmuramoylalanine--D-glutamate ligase
  • EC number
  • Alternative names
    • D-glutamic acid-adding enzyme
    • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
  • Recommended name
    UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase
  • EC number
  • Alternative names
    • UDP-MurNAc-L-Ala-L-Glu epimerase

Gene names

    • Name
      murD
    • Synonyms
      murL
    • ORF names
      COZ26_01110

Organism names

Accessions

  • Primary accession
    A0A2M7MHR4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain493-599Mur ligase central
Domain655-774Mur ligase C-terminal

Sequence similarities

Belongs to the MurCDEF family.
Belongs to the MurL family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    799
  • Mass (Da)
    92,315
  • Last updated
    2018-04-25 v1
  • Checksum
    AC6C140EB9F013AD
MPEKIFKFDNYNFNPASGIAVFGYSLDKIKFKEKLIFPKPIKKLIGARKKAFNKALFNLFLITGISYYKTYCPKKIELGKYKISKEQAKFWNKVYTKGLGQFFYENRLDFRGLIDFPYHKNYQEKPVKIKTRNRSLVPLGGGKDSIVVLEKMKENGIDFDLSHIGDSKIVNDVAKKSGKKIIFVKRKISPNLFSLNKKKGVYNGHIPISACHAFILLVRAILYDYRYIVMGNEKSSSYGNIKYLGTTINHQWSKSAEFEKMFSNYLKKFITPNIRYYSFLRNWDDLAITKEFVKHKKYFPVFSSCNKNFKLKGKAKNHWCNDCPKCVFTFTMLSAYLSEKELVDIFGKNLYQERKLKPLFDQLLGKEKFKPFECVGTPEAMKKAMAMARKKILILGFAREGLSSYKYLRKKYRQQLITIADAKKLSEFDKKYRDILKKDKNLELKLGKNYLKNLDKYNLIIKTAGIKLNKKNIHITTNLNIFLENIQGKIIGVTGTKGKSTTASLIDSILKAANKKVVLVGNIGKPFLDYLKLDSKNTIYVAELSSHQLDTLKGGLDVGVFTSFYPEHLDYHGNLKNYWQAKMNLVKNSKIIIVNKKIKKINRKKISYGPVKIKASLLGRHNQENIAAAMAVAKLFKIKKNIINKTIKNFKPLEHRLEYVGKYKNINFYNDVLSTTPESTMEAINALQRKNLQTIIVGGFDRGLDYKNLAKKIVSARIKNVIYWPHTGEKIIREIKKIKSEFRPNLIAVKNMEQTIKTAYKYTPANFTVLLSPAAASYNFYQNYQEKGKEFKKLVKKFG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PFJV01000025
EMBL· GenBank· DDBJ
PIX92577.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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