A0A2M7ILJ5 · A0A2M7ILJ5_9BACT
- ProteinMultifunctional fusion protein
- GenemurD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids799 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
Catalytic activity
- UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + ADP + phosphate + H+
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 495-501 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | racemase and epimerase activity, acting on amino acids and derivatives | |
Molecular Function | tetrahydrofolylpolyglutamate synthase activity | |
Molecular Function | UDP-N-acetylmuramoylalanine-D-glutamate ligase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended nameUDP-N-acetylmuramoylalanine--D-glutamate ligase
- EC number
- Alternative names
- Recommended nameUDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Candidatus Kuenenbacteria
Accessions
- Primary accessionA0A2M7ILJ5
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 493-599 | Mur ligase central | |||
Domain | 655-774 | Mur ligase C-terminal | |||
Sequence similarities
Belongs to the MurCDEF family.
Belongs to the MurL family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length799
- Mass (Da)92,301
- Last updated2018-04-25 v1
- ChecksumA890CAC16AAFCE3D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PFHP01000047 EMBL· GenBank· DDBJ | PIW95638.1 EMBL· GenBank· DDBJ | Genomic DNA |