A0A2L0H3P8 · A0A2L0H3P8_RHIFR

Function

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.
Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.

Features

Showing features for active site.

148550100150200250300350400450
TypeIDPosition(s)Description
Active site251Proton acceptor
Active site273Proton donor

GO annotations

AspectTerm
Molecular FunctionNAD binding
Molecular Functionprecorrin-2 dehydrogenase activity
Molecular Functionsirohydrochlorin ferrochelatase activity
Molecular Functionuroporphyrin-III C-methyltransferase activity
Biological Processcobalamin biosynthetic process
Biological Processmethylation
Biological Processsiroheme biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Siroheme synthase
      (EC:4.99.1.4
      )

Gene names

    • Name
      cysG
    • ORF names
      NXT3_CH01534

Organism names

  • Taxonomic identifier
  • Strain
    • NXT3
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Sinorhizobium/Ensifer group > Sinorhizobium

Accessions

  • Primary accession
    A0A2L0H3P8

Proteomes

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain154-211Sirohaem synthase dimerisation
Domain221-430Tetrapyrrole methylase
Region462-485Disordered

Sequence similarities

Belongs to the precorrin methyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    485
  • Mass (Da)
    51,675
  • Last updated
    2018-04-25 v1
  • Checksum
    88699A33DC2EB96C
MSQQLSVFPAFFRVAQKSVAVFGNGDEAFAKVRLLLNTEARILAYADHPEPAFAAFLEDKGIETVREAFADHQVEGAALVFAATGDAAADRVIVTAARERKVPANAVDQPDYCDFLTPALVNRAPVAIAIGTEGAGPVLAQMIRAQIDQLLSPSLGIVATLAASYREAVDRLIPRGVARRVFWRRFFSGPVADHVALGDLASARREASRLLDATERVSGHVWLVGAGPGAEDLLTLRAQRVMMEADAIVYDALVPQAIVDMGRRDAERLSVGKRKGCHTKSQDEINHLLVKLAKEGKRVVRLKSGDPLIFGRAGEEMAAMREAGVSYEIVPGITSAFAAAADFELPLTLRGVASSLVFTTGHDLAGDVLPDWARLAVSGATIAVYMGRSVAASVAGRLMQAGLPAETTVAVIENASRPERRLLHGILRELPDLENRTELDGPVMVIIGDAVAGARFDRSEPLAAGRRKGAGPSASGAHRAEHILN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024307
EMBL· GenBank· DDBJ
AUX76116.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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