A0A2K8SR27 · A0A2K8SR27_9NOSO
- ProteinNAD(P)H-quinone oxidoreductase chain 4
- GenendhD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids562 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
Catalytic activity
- a plastoquinone + NADH + (n+1) H+(in) = a plastoquinol + NAD+ + n H+(out)
a plastoquinone RHEA-COMP:9562 + CHEBI:57945 + (n+1) H+ (in)CHEBI:15378= a plastoquinol RHEA-COMP:9561 + CHEBI:57540 + n H+ (out)CHEBI:15378 - a plastoquinone + NADPH + (n+1) H+(in) = a plastoquinol + NADP+ + n H+(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane-derived thylakoid membrane | |
Cellular Component | respiratory chain complex I | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | NADH dehydrogenase activity | |
Molecular Function | ubiquinone binding | |
Biological Process | ATP synthesis coupled electron transport | |
Biological Process | electron transport coupled proton transport |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD(P)H-quinone oxidoreductase chain 4
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Nostocaceae > Nostoc
Accessions
- Primary accessionA0A2K8SR27
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cellular thylakoid membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-27 | Helical | |||
Transmembrane | 34-54 | Helical | |||
Transmembrane | 80-103 | Helical | |||
Transmembrane | 115-133 | Helical | |||
Transmembrane | 139-157 | Helical | |||
Transmembrane | 169-193 | Helical | |||
Transmembrane | 213-235 | Helical | |||
Transmembrane | 247-264 | Helical | |||
Transmembrane | 276-295 | Helical | |||
Transmembrane | 307-325 | Helical | |||
Transmembrane | 337-355 | Helical | |||
Transmembrane | 376-393 | Helical | |||
Transmembrane | 413-436 | Helical | |||
Transmembrane | 490-507 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 133-421 | NADH:quinone oxidoreductase/Mrp antiporter membrane subunit | |||
Sequence similarities
Belongs to the complex I subunit 4 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length562
- Mass (Da)61,297
- Last updated2018-04-25 v1
- Checksum270995527D2C42D0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP024785 EMBL· GenBank· DDBJ | AUB37924.1 EMBL· GenBank· DDBJ | Genomic DNA |