A0A2K6P4Q4 · A0A2K6P4Q4_RHIRO

Function

Catalytic activity

Features

Showing features for binding site.

135150100150200250300350
TypeIDPosition(s)Description
Binding site73ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentacrosomal vesicle
Cellular Componentaxoneme
Cellular ComponentcAMP-dependent protein kinase complex
Cellular Componentcentrosome
Cellular Componentciliary base
Cellular Componentcytosol
Cellular Componentglutamatergic synapse
Cellular Componentmitochondrion
Cellular Componentneuromuscular junction
Cellular Componentnuclear speck
Cellular Componentperinuclear region of cytoplasm
Cellular Componentplasma membrane raft
Cellular Componentpostsynapse
Cellular Componentsperm flagellum
Molecular FunctionAMP-activated protein kinase activity
Molecular FunctionATP binding
Molecular FunctioncAMP-dependent protein kinase activity
Molecular Functionmagnesium ion binding
Molecular Functionmanganese ion binding
Molecular Functionprotein domain specific binding
Molecular Functionprotein kinase A regulatory subunit binding
Molecular Functionprotein kinase binding
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine/tyrosine kinase activity
Molecular Functionubiquitin protein ligase binding
Biological Processadenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Processadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Processcellular response to cold
Biological Processcellular response to glucagon stimulus
Biological Processcellular response to glucose stimulus
Biological Processcellular response to heat
Biological Processcellular response to parathyroid hormone stimulus
Biological Processmesoderm formation
Biological ProcessmRNA processing
Biological Processnegative regulation of glycolytic process through fructose-6-phosphate
Biological Processnegative regulation of smoothened signaling pathway
Biological Processnegative regulation of TORC1 signaling
Biological Processneural tube closure
Biological Processpeptidyl-serine phosphorylation
Biological Processpositive regulation of cholesterol biosynthetic process
Biological Processpositive regulation of gluconeogenesis
Biological Processpositive regulation of insulin secretion
Biological Processpositive regulation of protein export from nucleus
Biological Processpostsynaptic modulation of chemical synaptic transmission
Biological Processprotein export from nucleus
Biological Processprotein kinase A signaling
Biological Processprotein localization to lipid droplet
Biological Processregulation of bicellular tight junction assembly
Biological Processregulation of cell cycle
Biological Processregulation of osteoblast differentiation
Biological Processregulation of proteasomal protein catabolic process
Biological Processregulation of protein processing
Biological Processsperm capacitation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    cAMP-dependent protein kinase catalytic subunit alpha
  • EC number

Gene names

    • Name
      PRKACA

Organism names

Accessions

  • Primary accession
    A0A2K6P4Q4

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain44-298Protein kinase
Domain299-351AGC-kinase C-terminal

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    351
  • Mass (Da)
    40,590
  • Last updated
    2018-03-28 v1
  • Checksum
    BF6D3ECD2614E5AB
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2K6P4R4A0A2K6P4R4_RHIROPRKACA338
A0A2K6P4S5A0A2K6P4S5_RHIROPRKACA343

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp